3D LINEAGE

3D Lineage provide data reconciliation, workflow and case management by implementing a process-focused system and aligning business processes to business rules and data.

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3D LINEAGE

Industry:
Enterprise Software Software

Address:
Naperville, Illinois, United States

Country:
United States

Status:
Active


More informations about "3D Lineage"

The role of 3D genome organization in development and cell ...

Jun 13, 2019 Specifically, we discuss the dynamics of 3D chromatin and genome organization during gametogenesis, embryonic development, lineage commitment and stem cell โ€ฆSee details»

Cell typeโ€“specific 3D-genome organization and โ€ฆ

Feb 26, 2025 3D organization of the genome plays a critical role in regulating gene expression. How 3D-genome organization differs among different cell types and relates to cell typeโ€“dependent transcriptional regulation remains unclear.See details»

The 3D Genome in Transcriptional Regulation and โ€ฆ

Ren and colleagues review principles of 3D genome organization in mammalian cells with a focus on the emerging relationship between genome organization and lineage-specific transcriptional regulation in directing stem cell fate.See details»

Architectural protein subclasses shape 3-D organization of โ€ฆ

Our analyses reveal that distinct combinations of architectural proteins shape the 3-D organization of mammalian genomes at different length scales for unique functional purposes during โ€ฆSee details»

The role of 3D genome organization in development and cell ...

Specifically, we discuss the dynamics of 3D chromatin and genome organization during gametogenesis, embryonic development, lineage commitment and stem cell differentiation, โ€ฆSee details»

Organization and function of the 3D genome - Nature

Oct 14, 2016 In this article the authors review current knowledge on chromatin architecture and the molecular mechanisms that underlie it. They discuss how three-dimensional (3D) organization of chromatin ...See details»

Advancements in Mapping 3D Genome Architecture - PMC

High throughput sequencing has become the method of choice for mapping 3D genome organization. SPRITE allows for mapping multiple simultaneous DNA interactions in a single โ€ฆSee details»

Lineage-specific 3D genome organization is โ€ฆ

Nov 22, 2023 IKAROS mediates long-distance interactions both within and across domains and compartments to assemble a lineage-specific 3D genome organization required for immune โ€ฆSee details»

Multiscale 3D genome reorganization โ€ฆ

Feb 17, 2023 Little is known about three-dimensional (3D) genome organization in skeletal muscle stem cells [also called satellite cells (SCs)]. Here, we comprehensively map the 3D โ€ฆSee details»

Architectural protein subclasses shape 3D organization of โ€ฆ

Jun 6, 2013 Knockdown of Smc1 or Med12 in embryonic stem cells results in disruption of spatial architecture and downregulation of genes found in cohesin-mediated interactions. We โ€ฆSee details»

3D genome organization | Scientific Reports - Nature

Dec 22, 2022 In this 3D Genome Organization Collection, several groups have presented technical developments that increase the resolution power to interrogate the structure of the โ€ฆSee details»

The role of 3D genome organization in disease: from โ€ฆ

Here we discuss, starting from chromosome level organization going down to single nucleotide changes, recent studies linking diseases or phenotypes to changes in the 3D genome โ€ฆSee details»

Three-dimensional genome architecture coordinates key โ€ฆ

Oct 16, 2023 Although lineage-specific genes have been identified in the mammary gland, little is known about the contribution of the 3D genome organization to gene regulation in the โ€ฆSee details»

Spatiotemporal 3D chromatin organization across multiple brain โ€ฆ

1 day ago However, the spatiotemporal organization of three-dimensional (3D) chromatin structure and its regulatory functions across different brain regions remain poorly understood.See details»

Comparing 3D Genome Organization in Multiple Species Using โ€ฆ

A new computational model called phylogenetic hidden Markov random field (Phylo-HMRF) allows us to reveal genome-wide evolutionary patterns of 3D genome organization based on multi โ€ฆSee details»

Lineage-specific 3D genome organization is assembled at multiple โ€ฆ

A generic level of chromatin organization generated by the interplay between cohesin and CTCF suffices to limit promiscuous interactions between regulatory elements, but a lineage-specific โ€ฆSee details»

Lineage-specific 3D genome organization is assembled at

Nov 22, 2023 A generic level of chromatin organization generated by the interplay between cohesin and CTCF suffices to limit promiscuous interactions between regulatory elements, but โ€ฆSee details»

Three-dimensional genome architecture coordinates key โ€ฆ

Nov 8, 2023 Although lineage-specific genes have been identified in the mammary gland, little is known about the contribution of the 3D genome organization to gene regulation in the โ€ฆSee details»

Functional associations of evolutionarily recent human genes โ€ฆ

Mar 17, 2024 Genome organization is intricately tied to regulating genes and associated cell fate decisions. Here, we examine the positioning and functional significance of human genes, โ€ฆSee details»

Spatiotemporal 3D chromatin organization across multiple brain โ€ฆ

1 day ago Elucidating the regulatory mechanisms underlying the development of different brain regions in humans is essential for understanding advanced cognition and neuropsychiatric โ€ฆSee details»