AMP THERAPEUTICS - ANTIMICROBIAL PEPTIDES
Antimicrobial peptides (AMPs) are found in virtually every species, from microbes to humans. They comprise the first line of defense against infection through the innate immune system. The AMPT portfolio of unique antimicrobial peptides overcomes many of the issues associated with AMPs as anti-bacterial therapeutics, most notably potency, spectrum, stability and toxicity. The unique mechanism of action of these compounds and the low rate of resistance development positions these molecules as the next generation of novel anti-bacterials. In addition to their potential as stand-alone therapeutics, the AMPT portfolio, in combination with EnBiotix’s engineered bacteriophage platform, further enhances the scope and capabilities of both platforms.
AMP THERAPEUTICS - ANTIMICROBIAL PEPTIDES
Industry:
Alternative Medicine Biotechnology Health Care Medical
Founded:
2009-01-01
Address:
Leipzig, Sachsen, Germany
Country:
Germany
Status:
Active
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AMP Therapeutics - Antimicrobial Peptides - Crunchbase
The AMPT portfolio of unique antimicrobial peptides overcomes many of the issues associated with AMPs as anti-bacterial therapeutics, most notably potency, spectrum, stability and toxicity. The unique mechanism of action of these compounds and the low rate of resistance …See details»
Antimicrobial peptides as therapeutics: Confronting delivery …
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The latarcin derived peptide (LDP)-nuclear localization sequence (NLS) derived CPPs is a dual action peptide with AMP and CPP ... Brandenburg K, Weindl G. Antimicrobial peptides and …See details»
Antiviral and antibacterial peptides: Mechanisms of action - PMC
Statics of the antimicrobial peptides. (A) Source of antimicrobial peptides (in total: 3569) and (B) animal derived antimicrobial peptide percentages (in total: 2600) in the antimicrobial peptide …See details»
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In this era of multi-drug resistance (MDR), antimicrobial peptides (AMPs) are one of the most promising classes of potential drug candidates to combat communicable as well as …See details»
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Nov 20, 2024 The rapid progress of antibiotic resistance among bacteria has prompted serious medical concerns regarding how to manage multidrug-resistant (MDR) bacterial infections. …See details»
Recent advances in antimicrobial peptide-based therapy
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Keywords: AMP, antimicrobial peptide, anti-infectives, antibiotic resistance, therapeutic agents. Introduction. The rapidly increasing resistance toward conventional antibiotics suggests that, …See details»
Antimicrobial Peptides, Their Production, and Potential …
The article reviews the literature on antimicrobial peptides (AMPs) that exhibit unique antimicrobial mechanisms, such as broad-spectrum activity, low development of antimicrobial resistance, and the ability to modulate the …See details»
Antimicrobial Peptides (AMPs): Roles, Functions and ... - Springer
Oct 23, 2019 Antimicrobial peptides (AMPs) are a crucial part of innate immunity that exist in the most of living organisms. In fact, AMPs have ability to incite the innate immune response and …See details»
Full article: Antimicrobial peptides as therapeutic …
Aug 12, 2020 The antimicrobial peptides (AMPs), also known as host defense peptides, have recently captured attention as innovative drug candidates for the treatment of infectious disease and as novel immunomodulatory therapies …See details»
Text-To-AMP: Antimicrobial Peptide Design Guided by Natural Text
Antimicrobial peptides (AMPs) are vital components of the natural immune system. With their broad-spectrum antibacterial properties, low resistance, and multifunctionality, they are …See details»
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Intense nonclinical and clinical research is today ongoing to evaluate antimicrobial peptides (AMPs) as potential next-generation antibiotics. Currently, multiple AMPs are assessed in late …See details»
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Nov 1, 2020 For examples, an antimicrobial peptide mBjAMP1 can completely kill the Gram-positive bacteria Staphylococcus aureus (S. aureus) within 30 min and the Gram-negative …See details»
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Oct 4, 2021 INTRODUCTION. The World Health Organization (WHO) reports that antibiotic resistance continues to increase worldwide and therefore warns that a period in which …See details»
deep-AMPpred: A Deep Learning Method for Identifying …
Jan 10, 2025 Antimicrobial peptides (AMPs) are small peptides that play an important role in disease defense. As the problem of pathogen resistance caused by the misuse of antibiotics …See details»
Explainable deep learning and virtual evolution identifies ...
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Engineering Selectively Targeting Antimicrobial Peptides - PMC
High-throughput assays can considerably increase the rate of AMP discovery and expand the amount of antimicrobial activity data available for uncovering the underlying associations …See details»
Antimicrobial Peptides: Innovative Strategies Against WHO-Priority ...
1 day ago This ongoing crisis underscores a vital need for innovative therapeutic strategies. This Research Topic aims to assess the potential of antimicrobial peptides (AMPs), including host …See details»
Revisiting the potential of natural antimicrobial peptides against ...
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