AMYGDALA NEUROSCIENCE
Amygdala Neurosciences is developing ANS-6637 a new chemical entity with a novel MOA for treating substance use disorder. Based on a mechanism of action in the brain (published in Nature Medicine) that prevents pathophysiologic dopamine surge without changes to basal dopamine, ANS-6637 has the potential to prevent drug seeking behavior, craving and relapse. In pre-clinical studies, ALDH2 inhibition reduced self-administration, cue- and drug-primed relapse in nicotine, alcohol, cocaine, heroin,... methamphetamine and binge eating models and also demonstrated anxiolytic properties in models of stress. ANS-6637 has completed extensive Phase 1 studies and is ready for Phase 2 efficacy studies. Their initial development focus is for smoking cessation with parallel development efforts for cocaine, opioid and alcohol use disorders.
AMYGDALA NEUROSCIENCE
Social Links:
Industry:
Biotechnology Health Care Neuroscience Online Portals Pharmaceutical
Founded:
2015-01-01
Address:
Palo Alto, California, United States
Country:
United States
Website Url:
http://www.amygns.com
Total Employee:
11+
Status:
Active
Email Addresses:
[email protected]
Total Funding:
6.95 M USD
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Current Employees Featured
Founder
Investors List
U.S. Department of Defense
U.S. Department of Defense investment in Series A - Amygdala Neuroscience
National Institutes of Health
National Institutes of Health investment in Series A - Amygdala Neuroscience
National Institutes of Health
National Institutes of Health investment in Grant - Amygdala Neuroscience
Asset Management Ventures (AMV)
Asset Management Ventures (AMV) investment in Seed Round - Amygdala Neuroscience
Asset Management Ventures (AMV)
Asset Management Ventures (AMV) investment in Venture Round - Amygdala Neuroscience
Official Site Inspections
http://www.amygns.com
- Host name: 186.221.184.35.bc.googleusercontent.com
- IP address: 35.184.221.186
- Location: United States
- Latitude: 38.6583
- Longitude: -77.2481
- Timezone: America/New_York
