DYNAMICS SPECIAL PURPOSE CORPORATION

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DYNAMICS SPECIAL PURPOSE CORPORATION

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Rowan Chapman
Rowan Chapman Chief Business Officer @ Dynamics Special Purpose Corporation
Chief Business Officer
2021-03-01

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Distearoylphosphatidylcholine - Wikipedia

Distearoylphosphatidylcholine is a phosphatidylcholine, a kind of phospholipid. It is a natural constituent of cell membranes, eg. soybean phosphatidylcholines are mostly different 18-carbon phosphatidylcholines (including minority of saturated DSPC), and their hydrogenation results in 85% DSPC. It can be used to prepare lipid nanoparticles which are used in mRNA vaccines, In particular, it forms paโ€ฆSee details»

Lateral organization and domain formation in a two-component โ€ฆ

The thermodynamic phase behavior and lateral lipid membrane organization of unilamellar vesicles made from mixtures of 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) and 1,2 โ€ฆSee details»

Distearoylphosphatidylcholine DSPC | Polysciences

Distearoylphosphatidylcholine (DSPC) is a zwitterionic phospholipid that is used in the preparation of liposomes for transfection and drug delivery applications. DSPC functions to enhance encapsulation efficiency and liposome stability โ€ฆSee details»

Study of Structural stability and formation mechanisms in DSPC โ€ฆ

The final structure of lipids of DSPC and DPSM after 1000 nanoseconds (1 microsecond). The formation of liposomes. In this study, density, gyration radius, Radial Distribution Function โ€ฆSee details»

Mechanical Properties Determination of DMPC, DPPC, โ€ฆ

Mar 16, 2020 Lipid bilayers are active participants in many crucial biological processes. They can be observed in different phases, liquid and solid, respectively. The liquid phase is predominant in biological systems. The solid โ€ฆSee details»

Nano-mechanical characterization of asymmetric DLPC/DSPC โ€ฆ

Jan 1, 2021 In this paper, we have examined the lateral organization and nano-mechanical properties of DLPC/DSPC SLBs. We have performed both AFM imaging and force โ€ฆSee details»

Ionizable Amino Lipids Distribution and Effects on โ€ฆ

Jul 27, 2023 Lipid nanoparticles (LNPs) containing ionizable aminolipids are among the leading platforms for the successful delivery of nucleic-acid-based therapeutics, including messenger RNA (mRNA). The two recently FDA โ€ฆSee details»

Mechanical Properties Determination of DMPC, DPPC, DSPC, and โ€ฆ

A .gov website belongs to an official government organization in the United States . Secure .gov websites use HTTPS ... The DSPC bilayer is measured below the subtransition ... Open 2013, โ€ฆSee details»

Comprehensive analysis of lipid nanoparticle formulation and ...

Interestingly, in an in vivo study comparing identical LNP formulations with either DOPE or DSPC as helper lipids, LNPs formulated with DOPE preferentially accumulated and exhibited better โ€ฆSee details»

Nanoscale Phase Separation in DSPCโ€“Cholesterol โ€ฆ

Jul 8, 2013 The lipid arrangement of eukaryotic cell membranes has been shown to be heterogeneous, with domains enriched in cholesterol and saturated phospholipids, coexisting with a continuous phase that is enriched in โ€ฆSee details»

1,2-Distearoyl-sn-glycero-3-phosphocholine - PubChem

Oct 14, 2021 HMDB is offered to the public as a freely available resource. Use and re-distribution of the data, in whole or in part, for commercial purposes requires explicit permission of the authors and explicit acknowledgment of the โ€ฆSee details»

Design of lipid-based nanoparticles for delivery of therapeutic โ€ฆ

Mar 1, 2023 Nowadays, DSPC is frequently used as the helper lipid in LNP-nucleic-acid commercial formulations (Table 2), although several groups reported that DOPE, instead of โ€ฆSee details»

1,2-Distearoyl-sn-glycero-3-phosphorylcholine (DSPC) - ABP Bio

Introduction. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (DSPC) is a phospholipid containing the saturated long-chain (18:0) stearic acid inserted at the snโ€“ 1 and snโ€“ 2 positions. It has โ€ฆSee details»

1,2-Distearoyl-sn-glycero-3-phosphocholine | 816-94-4

Nov 20, 2024 1,2-Distearoyl-sn-glycero-3-PC (DSPC) is a phospholipid containing the saturated long-chain (18:0) stearic acid inserted at the sn-1 and sn-2 positions. It is commonly used in โ€ฆSee details»

and Hydration Properties of Distearoylphosphatidylcholine: a โ€ฆ

The phase behavior and hydration properties of DSPC in the presence of PSO 4 and compare them with the results for DPPC. 2 Materials and Methods 2.1 Materials DSPC of 99๏ผ… purity โ€ฆSee details»

DSPC | 816-94-4 - BroadPharm

DSPC (1,2-distearoyl-sn-glycero-3-phosphocholine) is a phosphatidylcholine with saturated tails. It has a melting temperature of ~54°C and a cylindrical geometry that allows DSPC molecules โ€ฆSee details»

Mechanical Properties Determination of DMPC, DPPC, DSPC, and โ€ฆ

The DSPC bilayer is measured below the subtransition, pretransition, and transition temper-atures (301, 324, and 328 K, respectively), which results in either an L c stable crystalline phase or a โ€ฆSee details»

1,2-Distearoyl-sn-Glycero-3-Phosphatidylcholine - Larodan

1,2-Distearoyl-sn-Glycero-3-Phosphatidylcholine, also known as [(2R)-2,3-Di(octadecanoyloxy)propyl] 2-(trimethylazaniumyl)ethyl phosphate, L-ฮฑ ...See details»

BIO Appoints Veteran Communications Leader Sarah Alspach as โ€ฆ

1 day ago Today, the Biotechnology Innovation Organization (BIO) named Sarah Alspach as its new executive vice president and chief communications officer. Alspach, a communications โ€ฆSee details»

What is DSPC network and how does it work? - OmicsForum

Jun 12, 2022 DSPC stands for debiased sparse partial correlation. It is an algorithm designed to build partial correlation networks based on a graphical LASSO model using a data-driven โ€ฆSee details»