ELEMENT GENOMICS
Element Genomics is a discovery stage biotechnology company, focused on finding breakthrough cures for severe human disease through the use of functional genomics and manipulation of the epigenome. The company was incorporated in 2015 and is based in Durham, North Carolina.
ELEMENT GENOMICS
Industry:
Biotechnology Health Care Health Diagnostics
Founded:
2015-01-01
Address:
Durham, North Carolina, United States
Country:
United States
Total Employee:
11+
Status:
Active
Contact:
650-380-0138
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More informations about "Element Genomics"
An Overview of Genome Organization and How We …
How the genome folds is particularly important for transcription because control DNA elements and their target genes are not always next to each other along the linear genome ... Smallwood A, Ren B. 2013. Genome organization and long …See details»
Genomic organization - Wikipedia
Organisms have a vast array of ways in which their respective genomes are organized. A comparison of the genomic organization of six major model organisms shows size expansion with the increase of complexity of the organism. There is a more than the 300-fold difference between the genome sizes of yeast and mammals, but only a modest 4- to 5-fold increase in overall gene number (see the figure on the right). However, the ratio of coding to noncoding and repetitive se…See details»
The relationship between genome structure and function
Nov 24, 2020 In this Review, Oudelaar and Higgs discuss the relationship between genome structure and gene regulation, with a focus on whether genome organization has an instructive …See details»
In silico discovery of repetitive elements as key …
Oct 11, 2023 The human genome gives rise to its own organization in the nucleus, where the folding of chromatin into intricate and hierarchical structures can be reflective and instructive of cell state. 1 Sequence itself contains the …See details»
An RNA-centric view of transcription and genome …
Oct 3, 2024 The HIV1 transcriptional activator (Tat) binds to a specific hairpin loop and bulge structure transcribed from the 5′ long terminal repeat of the HIV1 genome, called the trans-activation response (TAR) element, to stimulate viral …See details»
Genome organization controls transcriptional dynamics …
Feb 3, 2022 The role of genome organization in the regulation of gene activity during development has been the subject of considerable controversy. Batut et al. present evidence that dedicated “tethering elements” help to establish long …See details»
Organization and function of the 3D genome - Nature
Oct 14, 2016 A key feature of vertebrate genomes is the relatively long distances along the linear genome separating cis-regulatory elements, ... the heterogeneity of 3D genome organization within a population ...See details»
The role of 3D genome organization in development and cell
Jun 13, 2019 The 3D organization of the genome is crucial for gametogenesis, embryogenesis and cell differentiation through its modulation of transcription, DNA replication and cell division. …See details»
9.1: Genomes and their organization - Biology LibreTexts
Typically mitochondrial genomes are ~16,000 base pairs in length and contain ~40 genes, while chloroplasts genomes are larger, ~120,000–170,000 base pairs in length, and encode ~100 …See details»
The Self-Organizing Genome: Principles of Genome …
Sep 24, 2020 The overall organization of genomes is strongly affected by their physical interaction with architectural elements of the cell nucleus, particularly the nuclear periphery and proteinaceous intranuclear bodies (Figure 2; Chen and …See details»
Transposable Elements, Epigenetics, and Genome Evolution
Nov 9, 2012 Transposable genetic elements (TEs) comprise a vast array of DNA sequences, all having the ability to move to new sites in genomes either directly by a cut-and-paste …See details»
Element Genomics - Crunchbase Company Profile & Funding
Element Genomics is a discovery stage biotechnology company, focused on finding breakthrough cures for severe human disease through the use of functional genomics and manipulation of …See details»
Transposable elements in mammalian chromatin organization
Jun 7, 2023 Transposable elements (TEs) and TE-derived sequences affect 3D genome architecture at multiple levels. a, TE-derived CCCT-C binding factor (CTCF) motifs delimit …See details»
Transposable Elements: Classification, Identification, and Their Use …
Jul 6, 2019 Most eukaryotic genomes contain large numbers of repetitive sequences. This phenomenon was described by Waring and Britten a half century ago using reassociation …See details»
Genome organization: Raison d’être of ancestral linkage groups
Jun 3, 2024 Importantly, most of the boundaries between different Nigon elements in the P. univalens germline genome correspond to the sites of chromosome breakage during PDE and …See details»
Element ratchets up race for cheaper DNA sequencing - STAT
Jan 11, 2023 Element’s machine can now read a whole human genome for as little as $200 — the cost of a couple trips to the grocery store. ... But genomics startup Element Biosciences on …See details»
BeetRepeats: reference sequences for genome and polymorphism …
6 days ago Objectives Despite the advances in genomics, repetitive DNAs (repeats) are still difficult to sequence, assemble, and identify. This is due to their high abundance and diversity, …See details»
Expanded encyclopaedias of DNA elements in the human and …
Jul 29, 2020 Across multiple data types, the increase in the scale of experimental data has provided new insights into genome organization and function, and catalysed new capabilities …See details»
The Self-Organizing Genome: Principles of Genome Architecture …
Oct 1, 2020 The overall organization of genomes is strongly affected by their physical interaction with architectural elements of the cell nucleus, particularly the nuclear periphery and …See details»
EPI-WIN digest 14 - World Health Organization (WHO)
Aug 27, 2024 The International Pathogen Surveillance Network (IPSN) is a global network of pathogen genomic actors, brought together by the WHO Hub for Pandemic and Epidemic …See details»