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More informations about "Embryo"

Self-organization of stem cells into embryos: A window โ€ฆ

Jun 7, 2019 Here, we review the principles of self-organization and how they set cells in motion to create an embryo. Vertebrate development deploys โ€ฆSee details»

Cells That Build Themselves Into an Embryo? Scientists โ€ฆ

Mar 20, 2025 Reference: โ€œSelf-organization of mouse embryonic stem cells into reproducible pre-gastrulation embryo models via CRISPRa programmingโ€ by Gerrald A. Lodewijk, Sayaka Kozuki, Clara J. Han, Benjamin R. Topacio, โ€ฆSee details»

Self-organization of a human organizer by combined โ€ฆ

May 23, 2018 The pioneering experiments of Spemann and Mangold demonstrated that a small group of cells located on the dorsal side of the early โ€ฆSee details»

Exploring Mechanical Forces Shaping Self-Organization and โ€ฆ

Embryonic development is a dynamic process orchestrated by a delicate interplay of biochemical and biophysical factors. While the role of genetics and biochemistry in embryogenesis has โ€ฆSee details»

From embryos to embryoids: How external signals and self โ€ฆ

The majority of aggregates that underwent proper self-organization showed a remarkable resemblance with post-implantation mouse embryos, which included the formation of localized โ€ฆSee details»

Principles of Self-Organization of the Mammalian โ€ฆ

Dec 10, 2020 In the mammalian embryo, the potential for self-organization is manifested in its extraordinary developmental plasticity, allowing a correctly patterned embryo to arise despite experimental perturbation. ... Adiyant โ€ฆSee details»

Nicolas Rivron Lab | Stem cells | Blastoid | Vienna

The academic research lab of Nicolas Rivron works on the self-organization of stem cells and created the blastoid, a complete model of the preimplantation mouse and human embryo. ... Synthetic embryo work could improve drugs โ€ฆSee details»

How DNA self-organizes in the early embryo | ScienceDaily

5 days ago The establishment of nuclear organization in mouse embryos is orchestrated by multiple epigenetic pathways. Cell , 2025; DOI: 10.1016/j.cell.2025.03.044 Cite This Page :See details»

Self-organization principles in stem-cell-derived โ€ฆ

Recently, in a work published in Nature Cell Biology, 5 we combine biophysical measurements, mathematical modeling, and functional perturbations to uncover the mechanisms of self-organization in ETX synthetic embryos. We discover โ€ฆSee details»

Mechanical forces as a signal in embryonic self-organization

Sep 25, 2024 This work will probably be a landmark study in our understanding of the interplay between biophysical processes and genetics in driving embryo formation. โ€” Timothy โ€ฆSee details»

Early embryos show surprising flexibility in fixing DNA โ€ฆ

6 days ago The establishment of nuclear organization in mouse embryos is orchestrated by multiple epigenetic pathways, Cell (2025). DOI: 10.1016/j.cell.2025.03.044.See details»

Self-organization of stem cells into embryos: A window on early ...

Here we focus on the principles of how cell communication at the molecular level enables embryonic self-organization in mouse and human embryos. ... Work in the laboratory of M.Z โ€ฆSee details»

The building blocks of embryo models: embryonic and ... - Nature

Apr 22, 2025 The process of a single-celled zygote developing into a complex multicellular organism is precisely regulated at spatial and temporal levels in vivo. However, understanding โ€ฆSee details»

Scientists program stem cells to mimic first days of embryonic ...

Mar 20, 2025 Their โ€œprogrammableโ€ embryo-like structures, also known as embryoids, can be used to study the role of certain genes in early development ... and their organization into an โ€ฆSee details»

Common principles of early mammalian embryo self-organisation

Jul 22, 2020 The ability of mammalian embryos to self-organise does not depend on any pre-patterning or any particular cues originating from the oocyte, as cleavage-stage embryos can โ€ฆSee details»

From embryos to embryoids: How external signals and self โ€ฆ

May 11, 2021 This perspective analyzes the different self-organizing processes observed in embryoid models, putting emphasis on symmetry breaking and self-assembly. Within this โ€ฆSee details»

The embryo as moral work object: PGD/IVF staff views and โ€ฆ

In performing this work, staff construct the embryo in a variety of forms of moral work object, allowing attention to shift between micro-level and overarching work goals, and away from a โ€ฆSee details»

Principles of Self-Organization of the Mammalian Embryo

Dec 10, 2020 Computational simulations on spatial organization of the embryo at this stage are in agreement with experimental observations to suggest that approximately 6 cells can be โ€ฆSee details»

The Self-Assembling Embryo: How Cells Talk to Build a Body, โ€ฆ

Jun 3, 2024 The self-assembling embryo In nature, self-organization is all around us: we can observe it in fish schools, bird flocks, or insect collectives, and even in microscopic processes โ€ฆSee details»

New insights into DNA organization during embryonic development

Sep 16, 2024 Researchers from the Kind Group have gained new insights into the mechanism behind the spatial organization of DNA within the cells of early embryos. When an embryo is โ€ฆSee details»