ENCYCLE THERAPEUTICS
Encycle Therapeutics is a Toronto-based biotech company exploiting a unique platform technology that enables the rapid synthesis of drug-like macrocycles or membrane-permeable nacellins. Nacellins have enormous potential to target intracellular protein-protein interactions, which are largely intractable to small molecule and biologic modulation, and can represent cheaper, oral equivalents to existing biologics (e.g., monoclonal antibodies). Encycle has collaborated with several pharmaceutical co... mpanies to complete a screening library of nacellins, many of which are cell-permeable and possess other drug-like properties. The company is also pursuing independent development of nacellins against integrin alpha-4-beta-7 (IBD) and SMURF2 (fibrosis); its lead program seeks to develop orally bioavailable inhibitors of integrin alpha-4-beta-7, which are safer and less immunogenic than marketed and investigational biologics targeting the same protein.
ENCYCLE THERAPEUTICS
Industry:
Biotechnology Chemical Therapeutics
Founded:
2012-01-01
Address:
Toronto, Ontario, Canada
Country:
Canada
Website Url:
http://www.encycletherapeutics.com
Total Employee:
1+
Status:
Active
Contact:
+1 (647) 258-4500
Total Funding:
6.07 M USD
Technology used in webpage:
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Current Advisors List
Board_member
Current Employees Featured
Jeffrey Coull President and CEO @ Encycle Therapeutics
President and CEO
Andrei Yudin Scientific Founder @ Encycle Therapeutics
Scientific Founder
Founder
Investors List
AcelRx Pharmaceuticals
AcelRx Pharmaceuticals investment in Venture Round - Encycle Therapeutics
BDC Capital Corporation
BDC Capital Corporation investment in Venture Round - Encycle Therapeutics
MaRS Investment Accelerator Fund
MaRS Investment Accelerator Fund investment in Venture Round - Encycle Therapeutics
Takeda Ventures
Takeda Ventures investment in Venture Round - Encycle Therapeutics
Toronto Innovation Acceleration Partners
Toronto Innovation Acceleration Partners investment in Venture Round - Encycle Therapeutics
CQDM
CQDM investment in Venture Round - Encycle Therapeutics
Ontario Centres of Excellence
Ontario Centres of Excellence investment in Seed Round - Encycle Therapeutics
Ontario Centres of Excellence
Ontario Centres of Excellence investment in Grant - Encycle Therapeutics
Official Site Inspections
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