ENCYCLE THERAPEUTICS

Encycle Therapeutics is a Toronto-based biotech company exploiting a unique platform technology that enables the rapid synthesis of drug-like macrocycles or membrane-permeable nacellins. Nacellins have enormous potential to target intracellular protein-protein interactions, which are largely intractable to small molecule and biologic modulation, and can represent cheaper, oral equivalents to existing biologics (e.g., monoclonal antibodies). Encycle has collaborated with several pharmaceutical co... mpanies to complete a screening library of nacellins, many of which are cell-permeable and possess other drug-like properties. The company is also pursuing independent development of nacellins against integrin alpha-4-beta-7 (IBD) and SMURF2 (fibrosis); its lead program seeks to develop orally bioavailable inhibitors of integrin alpha-4-beta-7, which are safer and less immunogenic than marketed and investigational biologics targeting the same protein.

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ENCYCLE THERAPEUTICS

Social Links:

Industry:

Biotechnology Chemical Therapeutics

Founded:

2012-01-01

Address:

Toronto, Ontario, Canada

Country:

Canada

Website Url:

http://www.encycletherapeutics.com

Total Employee:

Status:

Active

Contact:

+1 (647) 258-4500

Email Addresses:

[email protected]

Total Funding:

6.07 M USD

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Current Advisors List

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Rafi Hofstein Chairman of the Board of Directors @ Encycle Therapeutics
Board_member

Current Employees Featured

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Jeffrey Coull
Jeffrey Coull President and CEO @ Encycle Therapeutics
President and CEO

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Andrei Yudin
Andrei Yudin Scientific Founder @ Encycle Therapeutics
Scientific Founder

Founder

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Andrei Yudin

Investors List

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Official Site Inspections

http://www.encycletherapeutics.com

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