FILGRASTIM AND PEGFILGRASTIM
Filgrastim and pegfilgrastim are a supportive part of treatment for many patients receiving cancer chemotherapy. Some cancer drugs, in addition to attacking the cancer, destroy the patient's white blood cells, which are extremely important in fighting infection. Consequently, these patients are prone to developing severe, and even life-threatening, infections. Filgrastim and pegfilgrastim restore the number of white blood cells and thus improve their ability to kill infecting micro-organisms.
FILGRASTIM AND PEGFILGRASTIM
Industry:
Health Care Pharmaceutical
Address:
Zürich, Zurich, Switzerland
Country:
Switzerland
Status:
Active
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More informations about "Filgrastim and Pegfilgrastim"
The Safety Profile of Filgrastim and Pegfilgrastim - PMC
Treatment for the bone pain included the use of non-narcotic analgesics but a few patients (7% pegfilgrastim and 12% filgrastim) did require narcotics. The safety and efficacy of pegfilgrastim …See details»
Filgrastim vs pegfilgrastim: A quality of life issue for children
Filgrastim with pegfilgrastim have shown similar efficacy. Comparable similarities in incidence and duration of severe febrile neutropenia and need for transfusions have also beenSee details»
The Prophylactic Use of Filgrastim in Patients with Breast Cancer
We endorse the recommendations published by the European Organization for the Research and Treatment of Cancer (EORTC) and the American Society of Clinical Oncology ... formulations …See details»
Pegfilgrastim - Wikipedia
Pegfilgrastim, sold under the brand name Neulasta among others, is a PEGylated form of the recombinant human granulocyte colony-stimulating factor (GCSF) analog filgrastim. [19] It …See details»
Pegfilgrastim - StatPearls - NCBI Bookshelf
Apr 12, 2020 Pegfilgrastim is a pegylated granulocyte colony-stimulating factor that is FDA-approved to decrease the risk of patients developing febrile neutropenia when receiving …See details»
Design Rationale and Development Approach for Pegfilgrastim as …
A .gov website belongs to an official government organization in the United States. Secure .gov websites use HTTPS A lock Locked padlock icon ... Green M. Use of filgrastim and …See details»
Sickle-cell crisis with pegfilgrastim and filgrastim - Medsafe
Mar 6, 2025 Sickle-cell crisis with pegfilgrastim and filgrastim. Published: 6 March 2025 Prescriber Update 46(1): 10–11 March 2025. Key messages. Sickle cell disease (SCD) is a …See details»
FILGRASTIM, PEGFILGRASTIM, LIPEGFILGRASTIM
Filgrastim, pegfilgrastim and lipegfilgrastim are not interchangeable. Pegfilgrastim and lipegfilgrastim are long-acting forms of filgrastim, given as a single dose per cycle of …See details»
Attachment: Product Information: Pegfilgrastim
Bone marrow. Pegfilgrastim has reduced renal clearance and prolonged persistence . in vivo. compared to filgrastim. Pegfilgrastim and filgrastim have been shown to have identical modes …See details»
Use of filgrastim and pegfilgrastim to support delivery of
The most recent guidelines from three international cancer organizations, the European Organization for Research and Treatment of Cancer, the American Society of Clinical …See details»
Pegfilgrastim: Uses, Dosage, Side Effects, Warnings - Drugs.com
Pegfilgrastim is a pegylated or long-acting form of recombinant G-CSF, which means that it stays in your body for longer and doesn't need to be administered as often. Pegfilgramstim is a type …See details»
DRUG NAME: Filgrastim - BC Cancer
Filgrastim (recombinant human granulocyte colony stimulating factor, rG-CSF) is a hematopoietic growth factor which regulates the production and function of neutrophils. Filgrastim controls …See details»
Comparison of filgrastim and pegfilgrastim to prevent ... - PubMed
Purpose: The aim of this study was to compare the effectiveness of prophylactic single fixed dose of pegfilgrastim and daily administration of filgrastim on febrile neutropenia (FN), severe …See details»
Pegfilgrastim versus filgrastim in the supportive care of heavily ...
Background: Pegfilgrastim is a pegylated long-acting recombinant form of G-CSF that extends the half-life and allows for once-per-cycle dosing, requiring less frequent dosing than …See details»
Pegfilgrastim versus filgrastim after high-dose chemotherapy and ...
Nov 11, 2009 Pegfilgrastim (PEG) is synthesized by adding a 20 kDa polyethylene glycol moiety to FIL. This process modifies the pharmacokinetics and pharmacodynamic proprieties: longer …See details»
The Combination of Pegfilgrastim and Filgrastim Improves the …
Nov 2, 2023 METHODS: To test the hypothesis that the combination of pegfilgrastim and filgrastim schedule has superiority, we retrospectively investigated a cohort of 107 lymphoma …See details»
Meta-analysis and indirect treatment comparison of …
Jun 14, 2017 Two of the most widely used G-CSFs available are short-acting filgrastim (FIL; Neupogen®; Amgen Inc., Thousand Oaks, CA) 17 and long-acting pegfilgrastim (PEG; …See details»
Filgrastim, lenograstim and pegfilgrastim in the mobilization of ...
Apr 11, 2014 Pegfilgrastim results from the addition of a monomethoxy PEG to filgrastim, decreasing its serum clearance and markedly increasing its half-life. In fact, the G-CSF can be …See details»
The Optimal Timing and Duration of Daily G‐CSF for the Primary ...
2 days ago The GEPARTRIO study compared FN incidence between primary preventive treatment to daily filgrastim (Days 5–10, for 6 days) and pegfilgrastim during TAC …See details»
Pegfilgrastim: the promise of pegylation fulfilled
It is remarkable that all of this has occurred over the last decade since the initial approval of filgrastim (G-CSF) [].While much work remains to further our understanding of the biology and …See details»