GITR
GITR Inc. develops therapies to enhance the immune system by enabling T cells to be more effective in attacking cancer cells.
GITR
Industry:
Biotechnology Pharmaceutical Therapeutics
Founded:
2011-01-01
Address:
Cambridge, Massachusetts, United States
Country:
United States
Total Employee:
1+
Status:
Active
Total Funding:
4.75 M USD
Current Employees Featured
Founder
Investors List
HealthCare Ventures
HealthCare Ventures investment in Venture Round - GITR
More informations about "GITR"
What Are GitHub Organizations, and Should You Use One? - How โฆ
Jul 3, 2023 Organization administrators can add members to the organization, giving them permissions to read and write to repositories in the org. With GitHub Enterprise, you can also โฆSee details»
GITR: Boosting T Cell Activation for Enhanced Cancer โฆ
Glucocorticoid-induced tumor necrosis factor receptor (GITR) is an immune checkpoint molecule that plays a crucial role in regulating T cell activation and survival. In recent years, GITR has โฆSee details»
GITR - Crunchbase Company Profile & Funding
Organization. GITR . Connect to CRM . Save . Summary. Financials. People. Technology. Signals & News. Similar Companies. ... GITR closed its last funding round on May 8, 2015 from a โฆSee details»
Glucocorticoid induced TNF receptor family-related protein (GITR) โฆ
Aug 1, 2021 As mentioned previously, GITR and GITR-L are present on a large variety of cell-types, each responding differently to the activation of the GITR-GITR-L dyad. In the immune โฆSee details»
Targeting GITR in cancer immunotherapy โ there is no perfect โฆ
In vivo, agonistic anti-GITR monoclonal Abs (mAbs), such as the anti-mouse GITR DTA-1 and the anti-human GITR MK-4166, were found to transiently increase intratumoral Treg proliferation โฆSee details»
Therapeutic antibody activation of the glucocorticoid โฆ
Feb 25, 2022 The tumor necrosis factor (TNF) receptor superfamily includes 29 receptors that mediate diverse signal transduction pathways involved in immune cell proliferation, apoptosis, and inflammation (1โ3).The glucocorticoid โฆSee details»
Pharmacological modulation of GITRL/GITR system: therapeutic ...
Introduction. Murine GITR (mGITR) is a receptor belonging to TNF receptor superfamily (TNFRSF) that has been identified 14 years ago (Nocentini et al., 1997).Two years later, the โฆSee details»
Gene structure and chromosomal assignment of mouse GITR, a
In the present study, we examined the genomic organization of the entire mouse GITR (mGITR) gene. The gene spans a 2543-bp region and consists of five exons (with a length ranging from โฆSee details»
Assembly and structural properties of glucocorticoid-induced TNF ...
Dec 4, 2007 Glucocorticoid-induced TNF receptor (GITR) and its ligand GITRL are recently described members of the TNF receptor/ligand families and are implicated in a wide range of โฆSee details»
GITR Is an Attractive Target for Immunotherapy - ESMO
Jun 4, 2019 Many patients still do not benefit from immune checkpoint blockade. Therefore, there is a need for targeting of alternative immune pathways. Glucocorticoid-induced tumour โฆSee details»
HERA-GITRL activates T cells and promotes anti-tumor efficacy ...
Jul 19, 2019 Background Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid โฆSee details»
The Rising Importance of GITR Agonists as Alternative I/O โฆ
Nov 30, 2020 GITR signaling is a strong immune modulator and this pathway is actively being studied in preclinical tumor models and human patients to enhance antitumor responses. โฆSee details»
New emerging targets in cancer immunotherapy: the role of GITR
Mar 5, 2020 Combined treatment with anti PD-1 and GITR-agonist mAbs was able to achieve long-term survival in mouse model of ovarian and breast cancer, stimulating IFN-ฮณ producing โฆSee details»
How to Create GitHub Organization From Scratch?
Jul 2, 2024 For creating a new organization on GitHub you have to follow the below steps. Step 1: Navigate to the New Organization Page. On the GitHub homepage, click on your profile โฆSee details»
GITR: a modulator of immune response and inflammation
GITR/GITRL system participates in the development of autoimmune/inflammatory responses and graft vs. host disease and potentiates response to infection and tumors. These effects are due โฆSee details»
GitHub Organizations: How to SetUp and Use Wisely
Jul 8, 2020 The creation of a GitHub organization is rather trivial on the other hand. On your homepage at GitHub , click on the the 'Create Organization' from the drop-down on top-left. . โฆSee details»
Best practices for organizations and teams using GitHub Enterprise ...
Aug 2, 2023 An organization can only be created for strictly separated legal entities or subsidiaries where developers are not allowed to discover each other or each otherโs work; โฆSee details»
Pharmacological modulation of GITRL/GITR system: therapeutic ...
Abstract. Glucocorticoid-induced TNFR-related (gitr) is a gene coding for a member of the TNF receptor superfamily.GITR activation by its ligand (GITRL) influences the activity of effector โฆSee details»
Git - Managing an organization
An organization is pretty easy to create; just click on the โ+โ icon at the top-right of any GitHub page, and select โNew organizationโ from the menu. Figure 125. The โNew organizationโ menu โฆSee details»