Ypso-Facto

Ypso-Facto will be attending the 9th edition of the Congrès France Bioproduction, taking place on March 19-20, 2025, at the International Congress Center in Tours. Workshop Spotlight: 📌 Title: Prediction of the impact of Critical Process Parameters on Critical Quality Attributes by statistical vs mechanistic models – Application to a viral protein purified by ion exchange chromatography 🎙 Speakers: Lucrèce Nicoud (Ypso-Facto) & Eric FORMA (Sanofi) Accurately predicting the impact of Critical Process Parameters (CPPs) on Critical Quality Attributes (CQAs) is essential for regulatory compliance, process robustness, and optimization. While statistical models are commonly used, they have limitations, including high experimental workload and limited predictive capability. In this workshop, we will showcase how mechanistic modeling, based on physico-chemical principles, offers a strong alternative—enhancing process understanding, scalability, and efficiency while reducing the need for extensive experimentation. This study, conducted in collaboration with Sanofi, highlights the advantages of mechanistic modeling for viral protein purification via ion exchange chromatography. Attending the event? Let’s connect! 📩 Contact us to book a meeting: contact@ypso-facto.com

Mechanistic Modeling and Chromatography with ENSAIA - Ecole Nationale Supérieure d'Agronomie et des Industries Alimentaires Last week, we hosted the second session of our Practical Workshop on Chromatography with ENSAIA students. 👉 This session focused on the application of mechanistic models in chromatography, combining theory and practice to better understand complex separation processes. A key case study was the separation of sugars using multi-column chromatography, where students explored how predictive modeling can be used to optimize purification strategies. These concepts were then applied in a practical session, allowing students to bridge the gap between simulation and real-world applications. A great opportunity to demonstrate how mechanistic modeling enhances process understanding and efficiency! 🎯

We are hiring: Business Development Manager – DACH Region As part of our growth strategy, we are expanding in the DACH region and looking for a Business Development Manager to drive our presence and customer engagement. Your Mission 🔹 Develop and nurture relationships with existing customers. 🔹 Identify and engage new prospects within the biopharma and pharmaceutical industries. 🔹 Understand customer challenges and demonstrate how Ypso-Facto’s expertise and solutions can address them. 🔹 Collaborate with internal teams (technical experts, consultants, and software developers) to ensure customer satisfaction. 🔹 Represent Ypso-Facto at industry events, conferences, and meetings in the DACH region. Do you have experience in the biopharma industry and a proven track record in business development or sales? Do you want to work in an innovative company at the intersection of science, technology, and business, contributing to a more sustainable future through innovation? If so, you might be our next collaborator! 🚀 📩 Apply now at careers@ypso-facto.com or on our website: https://lnkd.in/esTK3fBn

New leadership, shared ambition "Nearly six years ago, we joined the Ypso-Facto journey, eager to contribute and learn from a company driven by science and innovation. What we found exceeded our expectations: a unique environment, remarkable people, and exciting challenges at the crossroads of chemistry, biology, and process engineering. Today, we are proud to take over the leadership of the company and continue the journey initiated by Roger-Marc. With complementary experiences—spanning industrial operations and scientific modeling—we are committed to driving forward our vision: helping the biopharmaceutical industry accelerate and secure its processes through a rigorous scientific approach. Mechanistic modeling is one of the most advanced expressions of this mindset—bringing clarity, efficiency, and robustness to process development—but it’s just one part of the broader expertise we aim to deliver. We look forward to shaping the next chapters of Ypso-Facto together with our talented team, trusted partners, and valued clients." Lucrèce Nicoud et Edouard Nicoud

Where to Meet Ypso-Facto Next? The Ypso-Facto team is gearing up for an exciting lineup of industry events! From bioprocessing to oligonucleotides, we’ll be attending key conferences across Europe. 📅 Save the dates & let’s connect! 🔹 12-14 March – NextGen Biomed by Oxford Global | London, UK 🔹 18-20 March – Bioprocessing Summit Europe | Barcelona, Spain 🔹 19-20 March – Congrès France Bioproduction | Tours, France 🔹 25-26 March – Annual Oligonucleotide Networking Group | Macclesfield, UK 🔹 29 April – Annual Oligonucleotide Symposium | Glasgow, Scotland 🔹 12-15 May – BioProcess International Europe | Hamburg, Germany If you're attending any of these events, we’d love to meet and discuss how we can support your bioprocessing challenges. Contact us to schedule a meeting : https://lnkd.in/e95bUm6E

[English below] Nous serons présents au Congrès France Bioproduction 2025, un rendez-vous clé pour les acteurs de la bioproduction. Contactez-nous dès maintenant pour planifier un échange sur place ! ------ We will be attending France Bioproduction Congress 2025, a key event for the bioproduction industry. Get in touch to schedule a meeting with our team!

Did you know Ypso-Facto is a family-owned company? For 10 years, under Roger-Marc Nicoud’s direction, three family members surrounded by a bunch of talented people worked together to build Ypso-Facto, driving growth and innovation. Now, the company is entering a new chapter, as Roger-Marc is stepping back from his role of CEO, letting Lucrèce Nicoud and Edouard Nicoud take the lead in continuing its development and building on this legacy. Roger-Marc Nicoud remains involved as a shareholder and advisor, contributing to the company’s journey while supporting its continued success. 👉 Read the full announcement here : https://lnkd.in/g6iFH8fU With a solid foundation and a shared vision, Ypso-Facto is ready to embrace the future !

🔬 Bioprocessing Challenges & Mechanistic Modeling 🔬 Quickly developing robust and efficient bioprocesses is a complex but essential task. Where do you see the biggest challenges that mechanistic modeling could help address? Vote below and feel free to share your thoughts in the comments! ⬇️ Looking forward to your insights! 💡 #bioprocessing #mechanisticmodeling #pharma #biotech #processdevelopment

🌟 Ever wanted to leverage mechanistic modeling but worried it’s too time-consuming? At Ypso-Facto, we understand that diving into mechanistic modeling can feel overwhelming—especially when time and expertise are in short supply. That’s why we created the Explore Package, the perfect solution to kick-start your journey with minimal effort and maximum impact. 🚀 What’s included? ✅ The selection of the mechanistic model adapted to your process. ✅ The determination of model parameters by our seasoned specialists. ✅ A practical demonstration of how the model can assess critical process parameters (CPPs) and their impact on critical quality attributes (CQAs). 💡 With the Explore Package, you’ll quickly see the potential of mechanistic modeling without needing to master the tools yourself. It’s efficient, results-driven, and designed to help you make data-backed decisions faster. From there, the possibilities grow: 👉 Expand the model’s capabilities to cover more phenomena. 👉 Exploit the insights for process characterization, optimization, and scale-up. 📩 Curious to see how this could transform your process development approach? Let’s talk! #MechanisticModeling #ProcessDevelopment #Innovation #YpsoFacto

This week, Kilian Kobl (Product Manager at Ypso-Facto) delivered a presentation at the IUT Robert SCHUMAN to third-year students, highlighting innovative chemical processes. He demonstrated how Proxima, our software suite, can be used to represent these processes and facilitate the establishment of mass balances, a crucial aspect for understanding and optimizing chemical processes. This session not only enriched the students' knowledge on the practical applications of chemical processes but also emphasized the importance of modern digital tools in chemical engineering. Thank you to all the participants for their interest!