KLOTHO THERAPEUTICS
KLOTHO Therapeutics (KTI) is a biotechnology company developing patent-pending Klotho proteins with great potential to redefine society’s experience with aging. Klotho, a naturally occurring human protein discovered in 1997, promises to delay major diseases of aging – kidney failure, Alzheimer’s, osteoporosis, cancer, hypertension and diabetes, according to published studies. For example, National Institutes of Health report Klotho-deficient animals live 25% shorter and look older while a... nimals overexpressing Klotho live 20-30% longer. The company’s first focus is on kidney failure, one of the major causes of death in the U.S. that affects up to 30 million people per year, 600,000 of whom are currently on dialysis. There is no successful long-term therapy today. KTI has filed patents on modified Klotho proteins covering its expansive potential indications.
KLOTHO THERAPEUTICS
Industry:
Biotechnology Health Care
Founded:
2016-07-19
Address:
San Diego, California, United States
Country:
United States
Website Url:
http://www.klotho.com
Total Employee:
1+
Status:
Active
Total Funding:
10 M USD
Technology used in webpage:
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Affimed
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Current Employees Featured
James Plante CEO, Chairman and Founder @ Klotho Therapeutics
CEO, Chairman and Founder
2017-10-01
Founder
Investors List
Thynk Capital, LLC.
Thynk Capital, LLC. investment in Series A - Klotho Therapeutics
Official Site Inspections
http://www.klotho.com
- Host name: aacb0a264e514dd48.awsglobalaccelerator.com
- IP address: 99.83.190.102
- Location: Seattle United States
- Latitude: 47.54
- Longitude: -122.3032
- Metro Code: 819
- Timezone: America/Los_Angeles
- Postal: 98108
More informations about "Klotho Therapeutics"
KLOTHO FOUNDATION - Google Sites
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KLOTHO FOUNDATION - ABOUT THE LEADERS - Google Sites
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Feb 20, 2023 The Structure and Function of Klotho. Klotho is a protein encoded by the klotho gene (Figure 1).The klotho protein can exist in either a membrane-bound form or a secreted, soluble form.See details»
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Klotho Therapeutics Summary. Company Summary. Overview. Klotho Therapeutics is a biotechnology company developing modified recombinant versions of the human protein …See details»
Klotho Company Profile 2025: Valuation, Funding & Investors
When was Klotho founded? Klotho was founded in 2021. Where is Klotho headquartered? Klotho is headquartered in Los Angeles, CA. What is the size of Klotho? Klotho has 4 total …See details»
Kidney Disease - Klotho Therapeutics Inc
Klotho is a single-pass transmembrane protein that is highly expressed in the kidney, brain, blood, and urine. This protein hormone is associated with a long, healthy life including healthy kidney function (Kuro-o et al., 1997).Clinical and …See details»
What Is Klotho? Understanding Its Role in Health and Disease
May 29, 2024 Klotho is a protein that affects aging and brain health. It can influence how long we live and how well our brains function. Researchers are exploring “what is klotho” to see if it can …See details»
Klotho: A protein that promotes healthy aging and improves …
May 7, 2025 Increasing levels of the secreted Klotho protein (s-KL) in mice extends lifespan by 15–20% and improves muscle, bone, and cognitive health during aging. Treated mice show …See details»
Molecular Basis of Klotho: From Gene to Function in Aging
The discovery of the α-Klotho gene has generated tremendous research interest that has significantly advanced our current understanding of the aging process.In humans, serum …See details»
New Insights Into The Anti-Aging Properties Of Klotho - Forbes
Aug 6, 2023 To understand the impact of Klotho at the cellular level, investigators also obtained a RAW264.7 tissue sample, known to express a particular type of inflammatory cell called …See details»
Klotho: Become Smarter And Live Longer With 50+ Ways To …
Feb 2, 2020 Klotho is an anti-aging protein that is mostly secrete by the kidneys, the brain, and the thyroid.R. It plays a major role in regulating kidney function and vascular health. R. The …See details»
Factors That Increase Klotho (Protein) + Gene Associations
Dec 15, 2022 What is Klotho (Protein)? Klotho is a protein that circulates in the blood and brain throughout life. It declines with age, in conjunction with cognitive deficits [1, 2, 3, 4].According …See details»
Anti-aging protein α-Klotho is potential for reducing ... - Nature
1 day ago This study investigated the impact of anti-aging protein α-Klotho on cardiometabolic diseases (CMDs) among middle-aged and elderly population. A total of 11,198 participants …See details»
Pathobiology of the Klotho Antiaging Protein and Therapeutic ...
The α-Klotho protein (henceforth denoted Klotho) has antiaging properties, as first observed in mice homozygous for a hypomorphic Klotho gene (kl/kl). These mice have a shortened …See details»
The Longevity Protein Klotho: A Promising Tool to Monitor …
The klotho protein has great potential to be used as a biological marker since a high serum level of klotho is associated with health and longevity . Three homologs of KL have been described: …See details»
What is Klotho and How Does it Work? - Peptide Sciences
Klotho and Neuroprotection. Beyond its roles in aging and kidney function, Klotho has demonstrated neuroprotective effects. Klotho is expressed in the brain, particularly in the …See details»