METABOLON
Metabolon is a technology company, develops analytical methods and software for biomarker discovery using metabolomics. It offers a biochemical profiling platform that analyzes and identifies biochemicals in the research of pharmaceutical, biotech, agriculture, cosmetic, and consumer products. Metabolon provides a unique, real-time fingerprint of biological system to reveal novel discoveries and realize the promise of precision medicine. The company can deliver an instantaneous snapshot of the ... entire physiology of a living being at a discreet point in time, as well as identify changes in that system brought about the impact of the disease, medical intervention, diet, or the environment. This deep and comprehensive view of the metabolome provides biological insights that cannot be revealed through any other research methodology, enabling life sciences researchers and drug developers to discover answers to some of biology’s most difficult questions. Metabolon was founded in 2000 and headquartered in Durham, North Carolina.
METABOLON
Industry:
Biotechnology Health Care Health Diagnostics Software
Founded:
2000-01-01
Address:
Durham, North Carolina, United States
Country:
United States
Website Url:
http://www.metabolon.com
Total Employee:
101+
Status:
Active
Contact:
919-572-1711
Email Addresses:
[email protected]
Total Funding:
159.7 M USD
Technology used in webpage:
Viewport Meta IPhone / Mobile Compatible SPF SSL By Default Google Font API LetsEncrypt Google Tag Manager WordPress Content Delivery Network Domain Not Resolving
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Current Advisors List
Current Employees Featured
Founder
Acquisitions List
| Date | Company | Article | Price |
|---|---|---|---|
| 2017-09-05 | Metabolomic Discoveries | Metabolomic Discoveries acquired by Metabolon | N/A |
| 2012-08-01 | Lipomics Technologies | Lipomics Technologies acquired by Metabolon | N/A |
Investors List
EW Healthcare Partners
EW Healthcare Partners investment in Venture Round - Metabolon
Perceptive Advisors
Perceptive Advisors investment in Venture Round - Metabolon
Essex Woodlands Healthcare Partners
Essex Woodlands Healthcare Partners investment in Venture Round - Metabolon
Camden Partners
Camden Partners investment in Series E - Metabolon
Fletcher Spaght, Inc.
Fletcher Spaght, Inc. investment in Series E - Metabolon
Fulcrum Equity Partners
Fulcrum Equity Partners investment in Series E - Metabolon
The Aurora Funds
The Aurora Funds investment in Series E - Metabolon
Sumitomo Corporation
Sumitomo Corporation investment in Series E - Metabolon
180 Degree Capital
180 Degree Capital investment in Series E - Metabolon
Syngenta Ventures
Syngenta Ventures investment in Series E - Metabolon
Newest Events participated
Participated in FiRe 2015
on 2015-10-06 as exhibitor
Key Employee Changes
Official Site Inspections
http://www.metabolon.com Semrush global rank: 2.46 M Semrush visits lastest month: 7.24 K
- Host name: 141.193.213.20
- IP address: 141.193.213.20
- Location: United States
- Latitude: 37.751
- Longitude: -97.822
- Timezone: America/Chicago
More informations about "Metabolon"
Metabolon – Small Molecules, Big Insights
At Metabolon, we offer the largest Level 1 library in the metabolomics industry. Our proprietary library has been built and curated over 20 years and contains over 5,400 entries. The vast …See details»
About Us - Metabolon
Metabolon deciphers thousands of discrete chemical signals from genetic and non-genetic factors to reveal biological pathways. We make connections where other omics cannot, and provide …See details»
Metabolon - Crunchbase Company Profile & Funding
Metabolon offers metabolomics solutions that enhance life sciences research, diagnostics, and precision medicine. Metabolon may be growing as it has recently secured an award from the NIH to develop diagnostics for PCOS, which …See details»
Metabolon - Products, Competitors, Financials, Employees, …
Metabolon specializes in metabolomics research and biomarker discovery within the biotecnology sector. The company offers services such as metabolite identification, biochemical pathway …See details»
Metabolon - Wikipedia
In biochemistry, a metabolon is a temporary structural-functional complex formed between sequential enzymes of a metabolic pathway, held together both by non-covalent interactions and by structural elements of the cell, such as integral membrane proteins and proteins of the cytoskeleton. The formation of metabolons allows the intermediate product from one enzyme to be passed (channelling)See details»
Metabolon formation regulates branched-chain amino acid
Nov 28, 2022 · Here, we analyse system-wide metabolomic changes in BCAT1- and BCAT2-deficient mouse models. Loss of BCAT2 but not BCAT1 leads to accumulation of BCAAs and …See details»
Resolving the metabolon: is the proof in the metabolite?
Aug 4, 2020 · In their current study, the Benkovic group provide direct proof by demonstrating that the six‐enzyme, two‐metabolite pathway within the purinosome is functional and that it promotes substrate channeling (Fig 1).See details»
Software - Metabolon
Metabolon’s software solutions empower researchers, clinicians, and scientists to navigate the intricate metabolomics landscape with precision and efficiency. Analyze your data faster with a …See details»
Organization of a functional glycolytic metabolon on ... - Nature
Sep 11, 2024 · Metabolons enhance metabolic efficiency by co-compartmentalizing enzymes with their sequential substrates, thereby minimizing diffusional transit times, promoting metabolite …See details»
Careers - Metabolon
Our company is a global highly cross-functional team spanning across R&D, Operations, Technology and AI, US and International Sales, Global Marketing and Administrative. Step into our world, where we offer a glimpse into the …See details»
Organization of a functional glycolytic metabolon on ... - PubMed
This study reveals a previously unappreciated pathway that links neuronal metabolism and mitochondrial function through OGT and the formation of the glycolytic metabolon, providing …See details»
Physical interactions among flavonoid enzymes in snapdragon and …
Feb 8, 2018 · However, how flavonoid enzymes are organized to form a metabolon is unknown for most plant species. We analyzed the physical interaction partnerships of the flavonoid …See details»
Direct Evidence for Metabolon Formation and Substrate …
Aug 24, 2016 · Supramolecular assembly of enzymes into metabolon structures is thought to enable efficient transport of reactants between active sites via substrate channeling.See details»
Membrane-bound metabolons - Nature Plants
Apr 30, 2018 · Metabolon-formation governs the biosynthetic efficiency of natural plant products. Identification of membrane-anchored proteins has now led to discovery of the metabolic …See details»
Metabolomics Analysis Services | Metabolon
Metabolon offers metabolomics services across the research continuum, from discovery to biomarker quantification and diagnostic test development. Our team of experts works with you …See details»
Metabolon - an overview | ScienceDirect Topics
A metabolon is a group of enzymes in a biosynthetic pathway that organizes spatially forming protein-protein interactions thereby generating a supramolecular complex with the ability to …See details»
Metabolons, enzyme–enzyme assemblies that mediate substrate …
Jan 11, 2021 · Metabolons are transient multi-protein complexes of sequential enzymes that mediate substrate channeling. They differ from multi-enzyme complexes in that they are …See details»
Bioinformatics - Metabolon
Metabolon’s Bioinformatics platform includes commonly used multivariate analyses; PCA, PLS-DA, Hierarchical clustering, Volcano Plot, and Pathway analysis.See details»
In vitro construction of the COQ metabolon unveils the molecular ...
Jan 3, 2024 · To elucidate the prerequisites for animal coenzyme Q biosynthesis, we sought to construct the entire metabolon in vitro. Here we show that this approach, rooted in ancestral …See details»
Role of Fatty Acids β-Oxidation in the Metabolic Interactions ...
1 day ago · In recent decades, several discoveries have been made that force us to reconsider old ideas about mitochondria and energy metabolism in the light of these discoveries. In this …See details»