MITOTIX
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More informations about "Mitotix"
Mitotix Company Profile 2024: Valuation, Investors, Acquisition
Developer of therapeutic products for the treatment of diseases resulting from inappropriate cell proliferation. The company's approach is based the mechanisms that regulate the cell division …See details»
Mitotix - Crunchbase Company Profile & Funding
Who are Mitotix's competitors? Alternatives and possible competitors to Mitotix may include Institut Merieux, Unilabs, and Probiotic Solutions. Mitotix is a Biotechnology company.See details»
Mitotix - insights.citeline.com
Sep 27, 1993 · Mitotix, based in Cambridge, Massachusetts, was established in 1992 to develop small molecule pharmaceuticals that selectively inhibit cell cycle targets. Disease targets …See details»
Germany-Based GPC Acquires Mitotix In All-Stock Transaction
Mar 21, 2000 · Germany-based GPC AG acquired Mitotix Inc. in an all-share transaction, creating a company that can more rapidly move from gene discovery to drug development. GPC …See details»
Mitotic spindle (DIS)orientation and DISease: Cause or consequence?
Correct alignment of the mitotic spindle during cell division is crucial for cell fate determination, tissue organization, and development. Mutations causing brain diseases and cancer in …See details»
On the Biotech Pharm, a Race to Harvest New Cancer Cures
Nov 7, 1997 · Scientists at Mitotix seek drugs to block inappropriate cell proliferation, cancer's hallmark. The potentially huge profits available to the inventors of better cancer drugs explain …See details»
Mitotic spindle assembly in animal cells: a fine balancing act
Feb 8, 2017 · Three microtubule nucleation pathways function in mitotic cells to contribute microtubules to the assembling spindle, namely the centrosome-, chromatin- and microtubule …See details»
Mechanisms of Mitotic Spindle Assembly - PMC - PubMed Central …
We follow with a discussion of the multiple MT nucleation pathways that play key roles in spindle assembly and how they are coordinated to generate a functional spindle.See details»
Mechanisms and Molecules of the Mitotic Spindle - Cell Press
Sep 21, 2004 · This process is facilitated by the intrinsic polarity and dynamic properties of microtubules and involves many proteins that modulate microtubule organization and stability. …See details»
Mechanobiology of the Mitotic Spindle - Cell Press
Jan 25, 2021 · In this Perspective, we discuss the advances in the understanding of spindle mechanics, focusing on microtubule forces that control chromosome movements. Segregation …See details»
Mitotic Spindle Organization by the Preprophase Band - Cell Press
In higher plants, the preprophase band (PPB) of microtubules (MTs) forecasts the cell division site prior to mitosis and specifies the organization of MTs into a bipolar prophase spindle …See details»
Eg5 UFMylation promotes spindle organization during mitosis
Jul 31, 2024 · Overall, Eg5 UFMylation is essential for proper spindle organization, mitotic progression, and cell proliferation. Ubiquitin-fold modifier 1 (UFM1) is a recently identified …See details»
Mitotic spindle | Nature Cell Biology
Jan 31, 2022 · Mitosis depends upon the action of the mitotic spindle, a subcellular machine that uses microtubules (MTs) and motors to assemble itself and to coordinate chromosome …See details»
2.2: The Mitotic Cell Cycle - Biology LibreTexts
We consider three of these modes: binary fission (used primarily by single celled bacteria and archaea), mitosis (used often by eukaryotes in processes of cell division NOT associated with …See details»
Organization of the Mitotic Chromosome | Science - AAAS
Nov 7, 2013 · In our polymer models, mitotic chromosome organization is described by two main features: arrays of consecutive 80- to 120-kb loops and linear ordering of loci separated by …See details»
Regulation of minimal spindle midzone organization by mitotic
Oct 29, 2024 · Coordinated by changes in the phosphorylation patterns of a multitude of microtubule associated proteins, the mitotic spindle first self-assembles to capture the …See details»
Mitotic spindle: lessons from theoretical modeling
Jan 28, 2021 · In this essay, we illustrate the lessons that emerge from the interplay of theory and experiments using examples from spindle mechanics, emphasizing how theory is useful also …See details»
Mitosis: a history of division | Nature Cell Biology
Mitosis has been studied since the early 1880s, to the extent that we now have a detailed, but still incomplete, description of spindle dynamics and mechanics, a sense of potential...See details»
What is a matrix organization and how does it work? - Asana
Feb 22, 2024 · What is a matrix organization and how does it work? A matrix organization is a company structure where teams report to multiple leaders. The matrix design keeps open …See details»
Counting mitoses: SI(ze) matters! | Modern Pathology - Nature
Jun 2, 2021 · In many publications, mitotic activity is given as a mitotic count, expressed as the number of mitoses per high-power field (HPF), or per 10 or 50 HPFs. High power is usually …See details»