NAIPS TECNOLOGIA

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Naips Tecnologia is focused on the development of web and mobile systems.

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NAIPS TECNOLOGIA

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Information Technology Mobile Software Web Development

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http://www.naips.com.br

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More informations about "Naips Tecnologia"

Inflammasome assembly: The wheels are turning | Cell Research

Nov 24, 2015 · Inflammasomes control host cell death and inflammation in response to sterile or infectious stimuli. Two recent reports published in Science reveal the structural basis for the …See details»

Domain organization and basic inflammasome …

The domains of AIM2, NAIPs, NLRC4, NLRP1, Pyrin, NLRP3, ASC, and CASP1 are shown. The archetype inflammasome structure is comprised of a sensor, adapter, and effector protein. After activation,...See details»

Inflammasomes: mechanism of assembly, regulation and signalling …

Jun 13, 2016 · Inflammasomes are multiprotein complexes that are assembled by pattern-recognition receptors following the detection of pathogenic microorganisms and danger signals …See details»

Structural basis of the human NAIP/NLRC4 inflammasome …

Jan 4, 2024 · Here we identify Bacillus thailandensis type III secretion system needle protein (Needle) as a potent trigger of the human NLR family apoptosis inhibitory protein …See details»

The NAIP/NLRC4 Inflammasomes - PMC

There is now clear evidence that NAIPs function as cytosolic innate immune receptors for specific bacterial protein ligands. Upon detection of these ligands, NAIPs co-assemble with a …See details»

The NAIP/NLRC4 inflammasomes - ScienceDirect

Feb 1, 2015 · There is now clear evidence that NAIPs function as cytosolic innate immune receptors for specific bacterial protein ligands. Upon detection of these ligands, NAIPs …See details»

Emerging concepts about NAIP/NLRC4 inflammasomes

Jul 1, 2014 · Neuronal apoptosis inhibitory protein (NAIP)/NOD-like receptor (NLR) containing a caspase activating and recruitment domain (CARD) 4 (NLRC4) inflammasome complexes are activated in response to proteins from …See details»

A) Domain organization of NAIPs and NLRC4 in mice.

Some NLRs, including NLRC4, can directly recruit caspase-1 via their caspase-recruitment domain (CARD), and activate it without ASC. In this case, NLRC4 is recruited to form the inflammasome...See details»

Structural basis of the human NAIP/NLRC4 …

Jan 4, 2024 · Here we identify Bacillus thailandensis type III secretion system needle protein (Needle) as a potent trigger of the human NLR family apoptosis inhibitory protein (NAIP)/NLRC4 inflammasome...See details»

Regional Technical Platform for Common Agricultural …

These NAIPs integrate social protection dimensions, food security and nutrition, gender and resilience among others, as central tools for translating CAADP goals into results at country level.See details»

Genetic functions of the NAIP family of inflammasome receptors …

Critical role of NAIPs in clearing bacterial infection and protecting mice from bacterial virulence–induced lethality. These re-sults provide definitive genetic evidence for the important …See details»

NAIP inflammasomes give the NOD to bacterial ligands - Cell Press

Oct 18, 2014 · NAIPs (NLR apoptosis inhibitory proteins) are NLR family members that contain NOD/NACHT, LRR, and 3 BIR domains (Figure 1A) . NAIPs are relatively unique among …See details»

The NAIP–NLRC4 inflammasome in innate immune detection of …

Apr 16, 2015 · Studies in the past 10 years have established a NAIP–NLRC4 inflammasome, in which NAIPs are cytosolic receptors for bacterial flagellin and T3SS rod/needle proteins, while …See details»

Bad germs are trapped | Cell Research - Nature

Jan 9, 2018 · Activation of the NAIP/NLRC4 inflammasomes initiates inflammatory responses against bacterial invasion. Two recent reports described the cryo-EM structure of the …See details»

Human NAIP and mouse NAIP1 recognize bacterial type III ... - PNAS

Aug 12, 2013 · Mice have multiple NAIPs that recognize flagellin (NAIP5/6) and T3SS rod proteins (NAIP2), as well as needle proteins (NAIP1). The presence of multiple NAIPs in mice, …See details»

Genetic functions of the NAIP family of inflammasome receptors …

Biochemical studies suggest that the NAIP family of NLR proteins are cytosolic innate receptors that directly recognize bacterial ligands and trigger NLRC4 inflammasome activation.See details»

Neuronal apoptosis inhibitory protein (NAIP) localizes to the ...

Jan 6, 2017 · The neuronal apoptosis inhibitory protein (NAIP) is a constituent of the inflammasome and a key component of the innate immune system. Here we use …See details»

Broad detection of bacterial type III secretion system and flagellin ...

Dec 12, 2017 · In mice, specific nucleotide-binding domain, leucine-rich repeat-containing family, apoptosis inhibitory proteins (NAIPs) act … Inflammasomes are cytosolic multiprotein …See details»

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