PROTEOSTASIS THERAPEUTICS
Proteostasis Therapeutics is discovering and developing novel small molecule therapeutics designed to control the body's protein homeostasis, or Proteostasis Network. The Proteostasis Network maintains the body's natural balance of proteins to protect us from numerous diseases. These novel therapies, or Proteostasis Regulators, are designed to treat multiple genetic and degenerative disorders associated with deficiencies of the Proteostasis Network, such as emphysema, type II diabetes, Alzheimer's Disease and Huntington's Disease.
PROTEOSTASIS THERAPEUTICS
Industry:
Biotechnology Medical Therapeutics
Founded:
2007-01-01
Address:
Cambridge, Massachusetts, United States
Country:
United States
Website Url:
http://www.proteostasis.com
Total Employee:
51+
Status:
Active
Contact:
6172257801
Total Funding:
105.01 M USD
Technology used in webpage:
SPF Domain Not Resolving Microsoft Exchange Online Office 365 Mail IPv6 ReCAPTCHA V2 Microsoft GlobalSign GlobalSign Domain Verification Akamai Hosted
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Current Advisors List
Board_member
Board_member
Board_member
Current Employees Featured
Janet Smart Senior Vice President, Legal Affairs @ Proteostasis Therapeutics
Senior Vice President, Legal Affairs
2020-03-01
Dean Richard Morimoto Founder @ Proteostasis Therapeutics
Founder
Marija Zecevic Chief Business Officer @ Proteostasis Therapeutics
Chief Business Officer
2017-04-01
Randall King Cofounder @ Proteostasis Therapeutics
Cofounder
2011-01-01
Geoffrey Gilmartin Chief Medical Officer @ Proteostasis Therapeutics
Chief Medical Officer
Ben Munoz Chief Scientific Officer @ Proteostasis Therapeutics
Chief Scientific Officer
2017-01-01
Helen Boudreau CFO @ Proteostasis Therapeutics
CFO
2017-07-01
Jeffery W. Kelly Co-Founder @ Proteostasis Therapeutics
Co-Founder
Sheila Wilson Vice President, Clinical Operations @ Proteostasis Therapeutics
Vice President, Clinical Operations
2016-01-01
Po-Shun Lee Chief Medical Officer and EVP @ Proteostasis Therapeutics
Chief Medical Officer and EVP
2014-01-01
Founder
Stock Details
Investors List
Cormorant Asset Management
Cormorant Asset Management investment in Series B - Proteostasis Therapeutics
Sanofi Ventures
Sanofi Ventures investment in Series B - Proteostasis Therapeutics
Novartis Venture Fund
Novartis Venture Fund investment in Series B - Proteostasis Therapeutics
HealthCare Ventures
HealthCare Ventures investment in Series B - Proteostasis Therapeutics
F-Prime Capital
F-Prime Capital investment in Series B - Proteostasis Therapeutics
Rock Springs Capital
Rock Springs Capital investment in Series B - Proteostasis Therapeutics
New Enterprise Associates
New Enterprise Associates investment in Series B - Proteostasis Therapeutics
Elan Corporation
Elan Corporation investment in Venture Round - Proteostasis Therapeutics
HealthCare Ventures
HealthCare Ventures investment in Series A - Proteostasis Therapeutics
Novartis Venture Fund
Novartis Venture Fund investment in Series A - Proteostasis Therapeutics
Official Site Inspections
http://www.proteostasis.com
- Host name: apache2-dap.pdx1-shared-a1-36.dreamhost.com
- IP address: 69.163.180.60
- Location: Brea United States
- Latitude: 33.9339
- Longitude: -117.8854
- Metro Code: 803
- Timezone: America/Los_Angeles
- Postal: 92821
More informations about "Proteostasis Therapeutics"
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Organization of the Proteostasis Network of Membraneless …
Nov 12, 2024 Organization of the Proteostasis Network of Membraneless Organelles Christine M. Lim 1, Yuqi Bian , Alicia González Díaz , Frank Pun2, Alex Zhavoronkov2, Richard I. …See details»
Activators of the 26S proteasome when protein degradation …
Jan 8, 2025 Among other modifications, ADP-ribosylation is known to stimulate the activity of the 20S proteasome upon H 2 O 2 treatment or neuroinflammatory stimulation, such as TNF-α …See details»
Pathways of cellular proteostasis in aging and disease - PMC
Klaips et al. outline the pathways and molecular mechanisms of cellular protein homeostasis, or proteostasis, and discuss how a decline in proteostasis during aging contributes to disease. ...See details»
Loss of proteostasis and age-related diseases | Lifespan.io
Aug 11, 2017 Proteostasis is the process that cells perform in order to have all their proteins functioning properly. Aging causes this process to fail, leading to diseases. ... Steve is the …See details»
Proteostasis restoration: a new metric for tau immunotherapy …
Jan 7, 2025 Proteostasis refers to the balance between protein synthesis, folding, modification and degradation. As all of these processes are disrupted in Alzheimer’s disease, 7 restoring …See details»
Protein Folding and Mechanisms of Proteostasis - PMC
This breakdown of proteostasis [89,91] can lead to a situation that is known as protein metastasis, ... The organization and evolutionary dynamics of the proteome provide a line of defense in …See details»