PURACYP

Puracyp is a biotechnology business committed to the development of technologies for assessing the safety of new medications quickly and efficiently before they are used in clinical trials. They provide cell-based platforms for studying nuclear receptor activation, which is the first step in the stimulation of drug-metabolizing enzymes. Human and rat PXR and AhR are among the nuclear receptor assays used in drug development. Other services include metabolic stability investigations, metabolism k... inetics, P450 reaction phenotyping, and P450 oxidation inhibition by novel chemical entities. They've designed methods that offer a high throughput while maintaining good quality. They also provide in vitro methods for studying oxidative drug metabolism, such as human liver microsomes with P450 enzyme expression profiles and antibodies to P450 enzymes.More