RIBOZYME PHARMACEUTICALS
Ribozyme Pharmaceuticals is a biotechnology company. It develops therapeutics based on RNA interference (RNAi) technology. The company provides research, preclinical, and clinical development services with product candidates in various areas including age-related macular degeneration (AMD), chronic hepatitis, dermatology, asthma, Huntington’s disease (HD), oncology, and diabetes. It offers Sirna-027, which completed phase I clinical trial and is used for the treatment of AMD; Sirna-034, ... which is under preclinical stage and is used for the treatment of hepatitis C virus; and various drugs under preclinical stage of development for asthma, HD, chronic hepatitis, diabetes, and dermatology. The company has strategic alliances with Allergan, Inc., Eli Lilly and Company, Targeted Genetics, Protiva, Archemix Corporation, and GlaxoSmithKline. Ribozyme Pharmaceuticals was founded in 1992 and is headquartered in San Francisco, California. As of March 5, 2014, it operates as a subsidiary of Alnylam Pharmaceuticals.
RIBOZYME PHARMACEUTICALS
Industry:
Biotechnology Health Care
Founded:
1992-01-01
Address:
Boulder, Colorado, United States
Country:
United States
Total Employee:
1+
Status:
Active
Total Funding:
12 M USD
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More informations about "Ribozyme Pharmaceuticals"
Ribozyme Pharmaceuticals - Crunchbase Company Profile & Funding
Ribozyme Pharmaceuticals is a biotechnology company. It develops therapeutics based on RNA interference (RNAi) technology. The company provides research, preclinical, and clinical development services with product candidates in various areas including age-related macular …See details»
Ribozyme Pharmaceuticals - Funding, Financials, Valuation
Ribozyme Pharmaceuticals is a biotechnology company that develops therapeutics based on RNA interference (RNAi) technology.See details»
Chris Christoffersen - President and CEO @ Ribozyme …
Previously, he was the President and CEO of Ribozyme Pharmaceuticals, Inc., a Morgenthaler portfolio biotechnology company with a mission to commercialize the Nobel Prize-winning …See details»
Reflections on Alnylam - Nature Biotechnology
May 9, 2022 · Sirna Therapeutics (né Ribozyme Pharmaceuticals) was born in early 2003 following a recapitalization of the business by a number of blue-chip investors, including …See details»
Nuclease-resistant synthetic ribozymes: developing a new class of ...
Nov 15, 2000 · RNA targets for ribozyme-based therapeutics may encode oncoproteins, growth factors, proinflammatory cytokines and their corresponding cell-surface receptors, and signal …See details»
Shoot the messenger: RNA editing is here - Nature Biotechnology
Mar 6, 2023 · RNA editing is rapidly gaining prominence as its transient and reversible changes promise a safer and more flexible option to reverse disease-causing mutations than DNA …See details»
RZNOMICS Inc. received FDA approval to initiate clinical …
Oct 25, 2022 · Ribozyme-based RNA editing technology developed by Rznomics has unique features, differentiating it from other nucleic acid-based editing approaches, as follows: (1) A …See details»
Ribozyme Pharmaceuticals Going Into Clinical Trials …
Jun 6, 2000 · Scientists from Ribozyme Pharmaceuticals Inc. (Boulder, CO) reported at the annual RNA Society Meeting in Madison on a new and proprietary ribozyme motif that has enhanced nuclease resistance, while maintaining …See details»
The Therapeutic Potential of Ribozymes | Blood - American Society …
Jan 15, 1998 · Ribozymes are catalytic RNA molecules that recognize their target RNA in a highly sequence-specific manner. They can therefore be used to inhibit deleterious gene expression …See details»
Development of ribozymes for gene therapy - PubMed
Ribozymes are a class of RNA molecules that can perform catalytically in the absence of protein. Specifically, they can hybridize to and cleave target RNA molecules independent of cellular …See details»
Ribozyme Pharmaceuticals - Crunchbase
Ribozyme Pharmaceuticals, Arrowhead Pharmaceuticals, Celator Pharmaceuticals, and Virscio are all part of the biotechnology sector. Ribozyme and Arrowhead focus on developing …See details»
Ribozymes - Latest research and news | Nature
A ribozyme is a ribonucleic acid (RNA) molecule with the ability to catalyze a biochemical reaction a function more commonly carried out by proteins.See details»
Ribozyme therapeutics - PubMed
Since their initial discovery, ribozymes have shown great promise not just as a tool in the manipulation of gene expression, but also as a novel therapeutic agent. This review discusses …See details»
Self-cleaving ribozymes: substrate specificity and synthetic biology ...
Various self-cleaving ribozymes appearing in nature catalyze the sequence-specific intramolecular cleavage of RNA and can be engineered to catalyze cleavage of appropriate substrates in an …See details»
Ribozyme Pharmaceuticals - Contacts, Employees, Board …
Ribozyme Pharmaceuticals has 1 current employee profile, President and CEO Chris Christoffersen. Ribozyme Pharmaceuticals is a biotechnology company that develops …See details»
Ribozymes: Nucleic acid enzymes with potential pharmaceutical ...
Jan 1, 2012 · This review briefly summarizes the ever increasing evidence to the use of ribozymes as innovative nucleic acid-based enzymes along with their classifications, their …See details»
Hunting for human ribozymes | Nature Chemical Biology
Mar 22, 2021 · Nature Chemical Biology - An approach based on enrichment of 5′ hydroxylated RNAs reveals a new self-cleaving ribozyme that maps to a very long non-protein-coding RNA …See details»
Ribozymes: Applications to Functional Analysis and Gene Discovery
Aug 1, 2004 · Ribozymes are catalytic RNA molecules that cleave RNAs with high specificity. Since the discovery of these non-protein enzymes, the rapidly developing field of ribozymes …See details»
Ribozymes, riboswitches and beyond: regulation of gene …
We first present an overview of ribozymes, riboswitches and other related RNA sensors, and highlight their impact on gene regulation. We then analyse their structure–function …See details»
Novel ribozymes: discovery, catalytic mechanisms, and the quest …
Aug 31, 2019 · We summarize the emerging principles of RNA catalysis as observed for small endonucleolytic ribozymes. Finally, we address the biological functions of those ribozymes, …See details»