SIMCHA THERAPEUTICS
Simcha Therapeutics is a biopharmaceutical company developing engineered cytokine immunotherapy for cancer. The company uses directed evolution to engineer novel cytokines designed to unlock the precision and power of the immune system. Simcha’s lead program, ST-067, is a designer IL-18 cytokine that has shown potent antitumor effects in animal models, both as a monotherapy and when combined with anti-PD-1 checkpoint inhibitors, as described in Nature in June 2020. It was founded in 2018 and is headquartered in New Haven, Connecticut, USA.
SIMCHA THERAPEUTICS
Social Links:
Industry:
Biotechnology Life Science Pharmaceutical Therapeutics
Founded:
2018-01-01
Address:
New Haven, Connecticut, United States
Country:
United States
Website Url:
http://www.simchatx.com
Total Employee:
1+
Status:
Active
Email Addresses:
[email protected]
Total Funding:
65 M USD
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Current Advisors List
Current Employees Featured
Founder
Investors List
SR One
SR One investment in Series B - Simcha Therapeutics
ArrowMark Partners
ArrowMark Partners investment in Series B - Simcha Therapeutics
BVF Partners
BVF Partners investment in Series B - Simcha Therapeutics
Logos Capital
Logos Capital investment in Series B - Simcha Therapeutics
Samsara BioCapital
Samsara BioCapital investment in Series B - Simcha Therapeutics
Rock Springs Capital
Rock Springs Capital investment in Series B - Simcha Therapeutics
Sequoia Capital China
Sequoia Capital China investment in Series A - Simcha Therapeutics
Connecticut Innovations
Connecticut Innovations investment in Series A - Simcha Therapeutics
Wuxi Venture Capital Group
Wuxi Venture Capital Group investment in Series A - Simcha Therapeutics
Official Site Inspections
http://www.simchatx.com Semrush global rank: 4.88 M Semrush visits lastest month: 1.8 K
- Host name: 93.26.196.104.bc.googleusercontent.com
- IP address: 104.196.26.93
- Location: United States
- Latitude: 38.6583
- Longitude: -77.2481
- Timezone: America/New_York

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The joy of new drug discovery Epitomized by our company name Simcha—a Hebrew word meaning joy—we are inspired by the opportunity to advance new medicines that can bring …See details»
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Aug 16, 2022 As Simcha continues to explore the breadth of ST-067’s potential in the clinic, and as we accelerate the advancement of other engineered cytokines, I feel privileged to build and …See details»
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View Simcha Therapeutics (www.simchatx.com) location in Connecticut, United States , revenue, industry and description. Find related and similar companies as well as employees by title and …See details»
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Simcha Therapeutics is a clinical-stage immunobiology company pioneering the development of first-in-class engineered cytokine therapeutics with transformational promise for patients. The …See details»
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Feb 28, 2025 Email ID: *****@simchatx.com; Key Metrics. Total Funding. $69.4M in 3 rounds. Latest Funding Round. Series B, Jan 27, 2022, $40M. Investors. Connecticut Innovations & 8 …See details»
Contact - Simcha Therapeutics
Looking for more information? Contact us at [email protected]. Our locations New Haven, CTNew York, NYSouth San Francisco, CASee details»
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Jan 28, 2022 Already A Biomedtracker Subscriber? You have access to the full company record through your subscription.See details»
Simcha Therapeutics - VentureRadar
Dansk Biotek Unknown n/a DANISH BIOTECH is a trade organization for Danish biotech companies with the aim to promote opportunities for biotechnology research, development and …See details»
Simcha Therapeutics Announces its Scientific Advisory Board, …
SOUTH SAN FRANCISCO, Calif., and NEW HAVEN, Conn., – August 22, 2023 – Simcha Therapeutics (“Simcha”), a clinical-stage immunobiology company pioneering first-in-class …See details»
Simcha Therapeutics, Inc. (Simcha Therapeutics, Inc.) - 药物管线_专 …
May 7, 2025 Studies will assess ST-067 in acute myeloid leukemia or myelodysplastic syndrome and in multiple myeloma Preclinical data to be presented at the 2024 American Society of …See details»
Simcha Therapeutics Accelerates Growth with Key Leadership …
Company Appoints Accomplished Biotech Leaders Sanuj Ravindran, M.D., as Chief Executive Officer and Jake Bauer as Independent Director and Chair NEW HAVEN, Conn., and SOUTH …See details»
Leadership Archives - Simcha Therapeutics
Tom worked at Amgen for 28 years and served in positions of increasing responsibility in growing Amgen Protein Sciences to an organization of over 300 researchers across five different sites. …See details»
News - Simcha Therapeutics
November 4, 2023. A phase 1/2 open-label, dose-escalation study of ST-067, a decoy-resistant IL-18 cytokine, given as a monotherapy and with pembrolizumab in advanced solid tumor …See details»