SPECKLE
Speckle is an ultra private FREE messaging app. Speckle uses your phone's Internet connection or WiFi to chat in real-time with friends, colleagues & family members. You can send and share images, videos, audio or pdf documents with an ease. • MULTIMEDIA: Send and receive photos, videos, documents, and Voice Messages. • FREE: Speckle uses your phone's Internet connection or Wi-Fi to let you message and call friends and family, so you don't have to pay for every message or call.* There ... are no subscription fees to use Speckle. • FREE CALLS: Call your friends and family for free, even if they're in another country.* Speckle calls use your phone's Internet connection rather than your cellular plan's voice minutes. (Note: Data charges may apply. Contact your provider for details.) • NO INTERNATIONAL CHARGES: There's no extra charge to send messages internationally. Chat with your friends around the world and avoid international SMS charges.* • GROUP CHAT: Enjoy group chats with your contacts so you can easily stay in touch with your friends or family. • PRIVACY: Speckle does not save or share data with 3rd party companies & agencies.
SPECKLE
Industry:
Android Apps Information Technology Internet Of Things IOS Messaging Mobile Social Media Software Telecommunications
Founded:
2017-01-01
Total Employee:
1+
Status:
Active
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More informations about "Speckle"
Nuclear Speckles: The Architecture of Gene Regulation
Apr 29, 2025 Nuclear architecture, including the positioning of nucleoli and Cajal bodies, also influences speckle organization. While nucleoli are primarily involved in ribosomal RNA …See details»
Genome organization around nuclear speckles drives mRNA
May 8, 2024 Gene organization around nuclear speckles is dynamic between cell types, and changes in speckle proximity lead to differences in splicing efficiency.See details»
Nuclear speckles – a driving force in gene expression
In this Review, we will summarize the current knowledge on nuclear speckle structure and function with respect to genome organization. Dynamic aspects …See details»
Genome organization around nuclear speckles drives mRNA
Gene organization around nuclear speckles is dynamic between cell types, and changes in speckle proximity lead to diferences in splicing eficiency.See details»
Nuclear speckle biology: At the cross-roads of ... - ScienceDirect
Dec 1, 2024 Here we provide a brief overview of nuclear speckle biology and biochemistry and then review the special role NS may play in organizing overall nuclear genome architecture. …See details»
Quantitative analysis of multilayer organization of proteins and …
Dec 12, 2017 In this model, spatially organized architectures result from spontaneous self-organization of nuclear speckle components through the interplay of sequence-encoded and …See details»
RNA molecules display distinctive organization at nuclear speckles
Figure 1. Intra-organelle RNA organization model with nuclear speckle as an example Nuclear proteins show differential localization with respect to nuclear speckles, with SRSF1 protein …See details»
CTCF/RAD21 organize the ground state of chromatin–nuclear …
Feb 21, 2025 The authors reveal that the chromatin architectural proteins CTCF and RAD21 organize DNA around nuclear speckles to enhance gene induction. This structural …See details»
Genome organization around nuclear speckles - PubMed
Nuclear speckles/IGCs are one of the most prominent nuclear bodies, yet their functional significance remains largely unknown. Recent advances in sequence-based mapping of …See details»
Dynamics of RNA localization to nuclear speckles are
Oct 16, 2024 We further reveal RNA sequence features contributing to transcript speckle localization, indicating a tight interplay between transcript speckle …See details»
Systematic mapping of nuclear domain-associated transcripts …
Mar 3, 2022 Furthermore, the significant overlapbetween the speckle marker-associated transcripts and TSA-seq-mapped speckle-proximal loci encoding these transcripts provides …See details»
Nuclear speckles: dynamic hubs of gene expression regulation
Jul 10, 2021 Nuclear speckle biology is almost exclusively studied in mammalian cells, where they have been first identified. In addition to mammalian cells, NS-like structures have been …See details»
Step-wise organization of genomic nuclear speckle-associated …
Feb 18, 2025 However, the dynamics of chromatin organization at nuclear speckles and their role in regulating gene activation during embryogenesis remain unexplored. To investigate …See details»
Nuclear speckles: molecular organization, biological function and …
Sep 1, 2017 Here, we discuss the functional implications of the localization of numerous proteins crucial for epigenetic regulation, chromatin organization, DNA repair and RNA modification to …See details»
Quantitative analysis of multilayer organization of proteins and …
Dec 15, 2017 Summary: Multi-color structured illumination microscopy imaging studies reveal a multilayer organization of nuclear speckles due to the interplay between favorable sequence …See details»
Nuclear speckles - a driving force in gene expression
Jul 1, 2022 Nuclear speckles are dynamic membraneless bodies located in the cell nucleus. They harbor RNAs and proteins, many of which are splicing factors, that together display …See details»
Quantitative analysis of multilayer organization of proteins and …
Nov 13, 2017 Coarse-grained simulations indicate that the non-random organization arises due to the interplay between favorable, sequence-encoded intermolecular interactions of speckle …See details»
Genome organization around nuclear speckles drives mRNA
Gene organization around nuclear speckles is dynamic between cell types, and changes in speckle proximity lead to differences in splicing efficiency. Finally, directed recruitment of a pre …See details»
TSA-seq reveals a largely conserved genome organization relative …
Dec 18, 2020 To test this “hardwiring” model of genome organization relative to nuclear speckles, here, we applied a more sensitive, “super-saturation” TSA-seq method to compare …See details»
3D genome organization around nuclear speckles drives mRNA
Jan 4, 2023 The nucleus is highly organized such that factors involved in transcription and processing of distinct classes of RNA are organized within specific nuclear bodies. One such …See details»