SPECKLE
Speckle is an ultra private FREE messaging app. Speckle uses your phone's Internet connection or WiFi to chat in real-time with friends, colleagues & family members. You can send and share images, videos, audio or pdf documents with an ease. • MULTIMEDIA: Send and receive photos, videos, documents, and Voice Messages. • FREE: Speckle uses your phone's Internet connection or Wi-Fi to let you message and call friends and family, so you don't have to pay for every message or call.* There ... are no subscription fees to use Speckle. • FREE CALLS: Call your friends and family for free, even if they're in another country.* Speckle calls use your phone's Internet connection rather than your cellular plan's voice minutes. (Note: Data charges may apply. Contact your provider for details.) • NO INTERNATIONAL CHARGES: There's no extra charge to send messages internationally. Chat with your friends around the world and avoid international SMS charges.* • GROUP CHAT: Enjoy group chats with your contacts so you can easily stay in touch with your friends or family. • PRIVACY: Speckle does not save or share data with 3rd party companies & agencies.
SPECKLE
Industry:
Android Apps Information Technology Internet Of Things IOS Messaging Mobile Social Media Software Telecommunications
Founded:
2017-01-01
Total Employee:
1+
Status:
Active
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More informations about "Speckle"
Nuclear speckles: molecular organization, biological function and …
Oct 13, 2017 Further studies on transcription and mRNA maturation and export revealed a more general role for splicing speckles in RNA metabolism. Here, we discuss the functional …See details»
Genome organization around nuclear speckles - ScienceDirect
Apr 1, 2019 The ‘nuclear speckle’ name is now reserved for one particular nuclear body, ranging in size from ∼0.3–3 μm and in number from several to tens per nucleus (Figure 1), as …See details»
Nuclear speckles: molecular organization, biological function and …
Sep 1, 2017 The gathering of NS proteins can be explained by the self-organization model, which is based on protein–protein and protein–RNA interactions. However, induction of NS …See details»
Nuclear speckles – a driving force in gene expression
It has been suggested that nuclear speckles are responsible for the positioning of genes with high GC content in the central part of the nucleus; in this way, they exert an important role in defining the increased GC content along the nuclear …See details»
RNA molecules display distinctive organization at nuclear speckles
May 5, 2024 Intra-speckle organization is not due to transcription order. Actively transcribed genes are found to be associated with speckle periphery. 17 One possible explanation for the …See details»
Nuclear speckles: a model for nuclear organelles
Aug 1, 2003 Figure 3: Modulation of transcription affects speckle organization. In transcriptionally active cells, pre-messenger RNA splicing factors localize in a speckled distribution pattern (left panel ...See details»
Nuclear speckle biology: At the cross-roads of ... - ScienceDirect
Here we provide a brief overview of nuclear speckle biology and biochemistry and then review the special role NS may play in organizing overall nuclear genome architecture. Finally, we then …See details»
Nuclear speckles: molecular organization, biological function and …
The functional implications of the localization of numerous proteins crucial for epigenetic regulation, chromatin organization, DNA repair and RNA modification to nuclear speckles are …See details»
Quantitative analysis of multilayer organization of …
Dec 15, 2017 The organization of U2 observed in our work was consistent with the previous studies of other speckle components, whereas SC35 remained in the speckle core in SON-depleted cells. All of these results strengthen our model …See details»
RNA molecules display distinctive organization at nuclear speckles
May 17, 2024 Intra-organelle RNA organization model with nuclear speckle as an example Nuclear proteins show differential localization with respect to nuclear speckles, with SRSF1 …See details»
Genome organization around nuclear speckles drives mRNA
The nucleus is highly organized, such that factors involved in the transcription and processing of distinct classes of RNA are confined within specific nuclear bodies 1,2.One example is the …See details»
Systematic mapping of nuclear domain-associated transcripts …
Transcripts preferentially labeled by the three APEX2-speckle markers show the highest degree of overlap with corresponding loci that, from TSA-seq mapping data, are the most proximal to …See details»
Nuclear speckles: dynamic hubs of gene expression …
Jul 10, 2021 Genome organization around NS In the last decade, significant advances have been made on how our genomes are organized in the interphase nucleus [ [ 41 ] ]. Leveraging advanced proximity-ligation methods such as Hi …See details»
Son Is Essential for Nuclear Speckle Organization and Cell Cycle ...
Jan 6, 2010 Proper nuclear speckle organization is important for coordinating transcription and pre-mRNA processing, because nuclear speckle integrity promotes cotranscriptional …See details»
RNA molecules display distinctive organization at nuclear speckles
Mar 28, 2024 Importantly, in both cases we observed the same intra-speckle RNA organization, in which the SRSF1 motif-rich region is closer to the speckle center than the hnRNPA1 motif …See details»
Nuclear speckles - a driving force in gene expression
Jul 1, 2022 Nuclear speckles are dynamic membraneless bodies located in the cell nucleus. They harbor RNAs and proteins, many of which are splicing factors, that together display …See details»
p53 mediates target gene association with nuclear speckles for ...
Apr 15, 2021 Regulated association between genes and nuclear speckles remains poorly understood. Alexander et al. find that the p53 transcription factor regulates speckle association …See details»
Single-cell measurement of higher-order 3D genome organization …
Aug 23, 2021 The percentage of cells containing centromere-proximal, speckle or nucleolar interactions is determined by looking through the filtered 1,000 single cells, focusing on …See details»