SPINDLE BIOTECH
Spindle Biotech is commercializing a proprietary RNA polymerase for large-scale mRNA vaccine production. Recent advances in mRNA technology have shown the growing importance of synthetic RNA in biological systems due to its desirable transient property.
SPINDLE BIOTECH
Industry:
Biotechnology Medical
Founded:
2017-06-28
Address:
Toronto, Ontario, Canada
Country:
Canada
Website Url:
http://www.spindle.bio
Total Employee:
1+
Status:
Closed
Email Addresses:
[email protected]
Technology used in webpage:
Nginx Namecheap DNS Namecheap Hosting
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http://www.spindle.bio
- Host name: 192.64.119.176
- IP address: 192.64.119.176
- Location: Los Angeles United States
- Latitude: 34.0318
- Longitude: -118.4252
- Metro Code: 803
- Timezone: America/Los_Angeles
- Postal: 90064
More informations about "Spindle Biotech"
Cell Biology: Size Scaling of Mitotic Spindles - PMC - PubMed …
Since then, the spindle has served as a paradigm for elucidating principles of organization and force production by macromolecule assembly/disassembly reactions. A fertile question has …See details»
Sliding filaments and mitotic spindle organization | Nature Cell …
Aug 1, 2014 Mitosis depends upon the action of the mitotic spindle, a subcellular machine that uses microtubules (MTs) and motors to assemble itself and to coordinate chromosome …See details»
The spindle: a dynamic assembly of microtubules and motors
Figure 4: Self-organization of microtubules and motors as a model for spindle-pole formation. Figure 5: A model for chromosome movement in Xenopus -extract spindles. Similar content …See details»
The Spindle: Integrating Architecture and Mechanics …
Aug 6, 2018 The spindle segregates chromosomes at cell division, and its task is a mechanical one. While we have a nearly complete list of spindle components, how their molecular-scale mechanics give rise to cellular-scale spindle …See details»
The Spindle | The Needleman Lab - Harvard University
The spindle is the paradigmatic self-organizing subcellular structure. It is made of microtubules, proteins which influence microtubule assembly and disassembly, molecular motors and cross …See details»
Mitotic spindle: lessons from theoretical modeling
Jan 28, 2021 Theories setting the stage for experiments are common in physics, but not so much in cell biology. In the spindle field, an exciting example is how a theoretical model led to the finding of spindle chirality. ... Microtubule …See details»
The Spindle: Integrating Architecture and Mechanics across Scales
Spindle self-organization connects scales from nanometers to tens of micrometers, and from tens of millise-condstoanhour.Therobustfunctionof thespindleemergesfromthe feedback …See details»
Interplay Between Spindle Architecture and Function
Jan 1, 2013 The fundamental structural unit of the spindle is the MT (Fig. 3.1), whose dynamics and organization are modulated by hundreds of MT-associated proteins (MAPs) and …See details»
Spindle architecture constrains karyotype evolution | Nature Cell …
Aug 8, 2024 They conclude that spindle organization dictates the available trajectories for karyotype evolution. Nature Cell Biology - Helsen et al. use experimental evolution and …See details»
Cell shape modulates mitotic spindle positioning forces via ...
2 days ago Such increase may have a functional implication for spindle stability during development, by maintaining a relative spindle centering precision mostly constant as cells …See details»
Current approaches for the analysis of spindle organization
Jul 4, 2019 The organization of microtubules in spindles is complex and not fully understood. Here we report on current advances in generating 3D reconstructions of staged spindles by …See details»
The Spindle: Integrating Architecture and Mechanics across Scales
The spindle segregates chromosomes at cell division, and its task is a mechanical one. While we have a nearly complete list of spindle components, how their molecular-scale mechanics give …See details»
Mitotic spindle | Nature Cell Biology
Jan 31, 2022 They conclude that spindle organization dictates the available trajectories for karyotype evolution. ... Nature Cell Biology (Nat Cell Biol) ISSN 1476-4679 (online) ISSN 1465 …See details»
Mechanism of spindle pole organization and instability in ... - Science
Using an RNA interference screen of proteins with diverse functions in spindle organization, we identified the molecular motor KIFC1 (kinesin superfamily protein C1) as a spindle-stabilizing …See details»
The cell cycle controls spindle architecture in Arabidopsis by ...
Aug 26, 2024 Romeiro Motta et al. show that spindle morphology is controlled by the phosphorylation of augmin performed by a cell-cycle regulator complex in Arabidopsis. By …See details»
Mitotic Spindle - Biology Simple
Apr 12, 2024 Mitotic Spindle Assembly: Investigating the molecular mechanisms that regulate the assembly and organization of the mitotic spindle can provide valuable insights into cell …See details»
What is spindle in biology? - ScienceOxygen
Sep 17, 2022 The spindle is a structure made of microtubules, strong fibers that are part of the cell’s “skeleton.” Its job is to organize the chromosomes and move them around during mitosis. …See details»
Mitotic spindle assembly in animal cells: a fine balancing act
Feb 8, 2017 Kleylein-Sohn, J. et al. Acentrosomal spindle organization renders cancer cells dependent on the kinesin HSET. J. ... The molecular biology of spindle assembly checkpoint …See details»
Spindle Biotech - Crunchbase Company Profile & Funding
Spindle Biotech has 2 investors including SOSV and SOSV. When was the last funding round for Spindle Biotech? Spindle Biotech closed its last funding round on Sep 29, 2022 from a Seed …See details»
Spindle positioning and its impact on vertebrate tissue ... - Nature
Jun 22, 2021 The orientation of cell divisions regulates tissue architecture and cell fate and depends on mitotic spindle positioning, which is controlled by intracellular and extracellular …See details»