WARBURG ONCOLOGY
Warburg Oncology develops novel and innovative therapeutic principles focusing on the inhibition of tumor-cell metabolism and immune evasion.
WARBURG ONCOLOGY
Industry:
Biotechnology Health Care Medical Oncology Therapeutics
Founded:
2021-01-01
Address:
Copenhagen, Hovedstaden, Denmark
Country:
Denmark
Status:
Active
Total Funding:
500 K EUR
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Investors List
BioInnovation Institute
BioInnovation Institute investment in Convertible Note - Warburg Oncology
More informations about "Warburg Oncology"
The Warburg effect: 80 years on - PMC - PubMed Central (PMC)
Influential research by Warburg and Cori in the 1920s ignited interest in how cancer cells' energy generation is different from that of normal cells. They observed high glucose consumption and …See details»
100 years of the Warburg effect: A cancer metabolism endeavor
Jul 25, 2024 Based on his findings, Warburg thought that cancer cells switched from an oxidative metabolism to a fermentative metabolism to ensure energy production. 9 Yet, while …See details»
Targeting the Warburg Effect in Cancer: Where Do We Stand?
To elucidate why cancer cells adopt the Warburg effect despite its apparent energetic disadvantage, it has been hypothesized that “the metabolism of cancer cells, and indeed all …See details»
The Warburg Effect: How Does it Benefit Cancer Cells? - PMC
A .gov website belongs to an official government organization in the United States. Secure .gov websites use HTTPS A lock ... Thompson CB. Metabolic reprogramming: a cancer hallmark …See details»
New Clarity on the Warburg Effect - NCI - National …
Jan 13, 2021 In the case of permitted digital reproduction, please credit the National Cancer Institute as the source and link to the original NCI product using the original product's title; e.g., “New Clarity on the Warburg Effect was …See details»
100 years of the Warburg effect: A cancer metabolism …
Jul 25, 2024 Based on his findings, Warburg thought that cancer cells switched from an oxidative metabolism to a fermentative metabolism to ensure energy production. 9 Yet, while intriguing, Warburg’s observation was not interesting …See details»
Warburg effect (s)—a biographical sketch of Otto …
Mar 8, 2016 The work of Otto Heinrich Warburg has been having a profound influence on the way we think about tumor metabolism. Particularly, in the field of cancer research, we are using the term “Warburg effect” to denote a metabolic …See details»
A century of the Warburg effect | Nature Metabolism
Nov 21, 2023 Warburg’s contributions provided the basis for the field of cancer metabolism and inspired a new cohort of researchers, who are making discoveries with the potential to realize …See details»
Cancer Signaling Drives Cancer Metabolism: AKT and …
Oct 1, 2021 Abstract. The Warburg effect, the propensity of some cells to metabolize glucose to lactate in the presence of oxygen (also known as aerobic glycolysis), has long been observed in cancer and other contexts of cell …See details»
The Warburg Effect: How Does it Benefit Cancer Cells?
Jan 5, 2016 Cancer cells rewire their metabolism to promote growth, survival, proliferation, and long-term maintenance. The common feature of this altered metabolism is the increased glucose uptake and fermentation of glucose to …See details»
Metabolic modelling links Warburg effect to collagen formation ...
6 hours ago Cancer cells are known to express the Warburg effect—increased glycolysis and formation of lactic acid even in the presence of oxygen—as well as high glutamine uptake. In …See details»
Otto Warburg's contributions to current concepts of cancer
Apr 14, 2011 Otto Warburg was a pioneering biochemistry researcher who made substantial contributions to our early understanding of cancer metabolism. Warburg was awarded the …See details»
The Warburg effect: 80 years on - ScienceDirect
Oct 19, 2016 Otto Warburg first described in the 1920s that cancer cells utilised higher levels of glucose in the presence of oxygen with an associated increase in lactate production. The …See details»
We need to talk about the Warburg effect | Nature Metabolism
Feb 3, 2020 That said, the Warburg effect is not a universal feature of proliferating cancer cells, even in culture. An analysis of more than 80 lung cancer cell lines found a nearly tenfold range …See details»
Targeting the Warburg Effect in Cancer: Where Do We Stand?
Mar 8, 2024 The Warburg effect, characterized by the preferential conversion of glucose to lactate even in the presence of oxygen and functional mitochondria, is a prominent metabolic …See details»
Biochemical Origin of the Warburg Effect in Light of 15 Years of ...
The Warburg effect is the hallmark of malignancy and differentiates energetics in hyperglycolytic cancer cells from normal cells. For the author, mitochondrial damage precedes the occurrence …See details»
The Warburg effect drives dedifferentiation through epigenetic ...
Dec 15, 2023 German biochemist and cell physiologist, Otto H. Warburg (), made a groundbreaking discovery in 1923.Specifically, tumors were shown to consume large amounts …See details»
Mechanism of the Warburg effect and its role in breast cancer ...
Nov 14, 2024 Breast cancer remains a significant global health concern affecting millions of women annually. An essential aspect of this disease is the Warburg effect, which is a …See details»
Scientists unveil the secret of cancer-associated Warburg effect
Oct 23, 2019 Scientists unveil the secret of cancer-associated Warburg effect. ScienceDaily . Retrieved November 27, 2024 from www.sciencedaily.com / releases / 2019 / 10 / …See details»
Warburg effect in colorectal cancer: the emerging roles in tumor ...
Nov 1, 2022 Colorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer-related death worldwide. Countless CRC patients undergo disease …See details»