LOWELL THERAPEUTICS

Lowell Therapeutics is a pharmaceutical company that develops products for critically ill patients. It develops an anticoagulant for critically ill patients in the ICU who experience kidney failure and need to go on an artificial kidney machine called continuous renal replacement therapy (CRRT), which is 24/7 dialysis. This machine involves circulating blood outside the patient through a filter. Eventually, blood will clot in the filter unless it is anticoagulated. When the filter clogs, doctors and nurses must stop the machine to change it – throwing away clotted blood and in the process, increasing blood loss and the need for transfusions.